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Autor:
Engin Ozcivici, Melis Olcum
Publikováno v:
Cancer Cell International
Ozcivici, Engin/0000-0003-4464-0475
PubMed: 25349533
Introduction: Mechanical loads can regulate cell proliferation and differentiation at various stages of development and homeostasis. However, the extension of this regulatory effect of me
PubMed: 25349533
Introduction: Mechanical loads can regulate cell proliferation and differentiation at various stages of development and homeostasis. However, the extension of this regulatory effect of me
Autor:
Aleida Olivares, Patricia Casas-González, Marco Allán Pérez-Solis, Arturo Aguilar-Rojas, Guadalupe Maya-Núñez
Publikováno v:
Cancer Cell International
Through research carried out in the last 25 years about the breast cancer etiology, it has been possible to estimate that less than 10 % of patients who are diagnosed with the condition are carriers of some germline or somatic mutation. The clinical
Autor:
Hossein Ghasemzadeh Kolagar, Soheila Yadollah-Damavandi, Mohammad Amin Azizi, Mohammad Amin Javidi, Tina Parsa, Ehsan Jangholi, Yekta Parsa, Seyed Abbas Mirmalek, Reza Alizadeh-Navaei, Seyed Alireza Salimi-Tabatabaee
Publikováno v:
Cancer Cell International
Background Breast cancer is the most prevalent malignancies among the women that have a high mortality. Previous studies demonstrated that hypericin, a bioactive component of Hypericum perforatum have a cytotoxic effect on the malignant cell lines. H
Publikováno v:
Cancer Cell International
Background Suberoyl bis-hydroxamic acid (SBHA) is a histone deacetylase (HDAC) inhibitor and exerts anti-growth effects in several malignancies including breast cancer. Proteasome inhibitors such as Bortezomib and MG-132 constitute novel anticancer a
Autor:
Jiong Wu, Mengying Liu, Shuling Zhou, Yayun Chi, Lin Yuan, Bingqing Zhou, Naisi Huang, Sheng Huang
Publikováno v:
Cancer Cell International
Background Accumulating studies have focused on the oncogenic and tumor suppressive roles of the newly identified lncRNAs. A novel lncRNA BC040587 in 3q13.31 locus which exists frequent copy number alterations was found to be associated with poor sur
Autor:
Liu-Mei Shou, Meng Shen, Kai Chen, Meng-Dan Xu, Min Jiang, Meng-Yao Wu, Wei-Ming Duan, Xiao Wu, Wei Li, Juan Hou, Min Tao, Fei-Ran Gong, Xiaojie Bian, Qiaoming Zhi
Publikováno v:
Cancer Cell International
Purpose Despite new developments in cancer therapy, chemotherapy and radiotherapy remain the cornerstone of breast cancer treatment. Therefore, finding ways to reduce the toxicity and increase sensitivity is particularly important. Tumor necrosis fac
Autor:
Xiao-Xu Liu, Meng Wang, Weili Min, Zhijun Dai, Huafeng Kang, Yong-Ping Shao, Xi-Jing Wang, Shuai Lin, Hong-Tao Ren, Yang Zhao
Publikováno v:
Cancer Cell International
Background Published data on the association between AURKA polymorphisms and breast cancer (BC) risk are inconclusive. This meta-analysis was performed to derive a more precise estimation on the relationship between AURKA polymorphisms (rs2273535 and
Autor:
Guan Liu, Dehong Zou, Xiangming He, Xuebing Yan, Xiangyun Zong, Hongjian Yang, Hua Xiang, Yang Yu
Publikováno v:
Cancer Cell International
Background Cell cycle regulatory pathway is a well-established pathway mainly dependent on cyclin-dependent kinases (CDKs), which are regulated positively by cyclins and negatively by cyclin-dependent kinase inhibitors(CKIs). Cyclin-dependent kinase
Autor:
Martina Schmiedlová, Kamila Balušíková, Jan Kovář, Jitka Stancikova, Vlasta Němcová-Fürstová, Ilaria Zanardi, Michael Jelinek, Jan Šrámek, Iwao Ojima
Publikováno v:
Cancer Cell International
Background In previous study we showed that caspase-2 plays the role of an apical caspase in cell death induction by taxanes in breast cancer cells. This study deals with the role of other caspases. We tested breast cancer cell lines SK-BR-3 (functio
Publikováno v:
Cancer Cell International
Background The specific mechanism underlying the contribution of the Aldehyde dehydrogenase 1 (ALDH1) phenotype to metastatic behavior and early tumor relapse in breast cancer is currently unclear. Methods 147 randomly selected invasive ductal carcin