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Publikováno v:
Cancer biomarkers : section A of Disease markers. 28(4)
Background Recurrence significantly influences the survival in patients with lung adenocarcinoma (LUAD). However, there are less gene signatures that predict recurrence risk of LUAD. Objective We performed this study to construct a model to predict r
Autor:
Chia-Lang Hsu, Yi-Nan Liu, Tzu-Hua Chang, Jin-Yuan Shih, Shang-Gin Wu, Hsin-Yi Wang, Yen-Ting Lin, Meng-Feng Tsai
Publikováno v:
Cancer biomarkers : section A of Disease markers. 28(3)
Background EGFR-mutant lung cancer inevitably develops resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). Objective To investigate the clinical relevance of microRNAs (miRNAs) in TKI therapy response and resistan
Publikováno v:
Cancer biomarkers : section A of Disease markers. 27(1)
Background Increasing evidence have shown that miRNAs play an important role in the development and progression of non-small cell lung cancer (NSCLC). Objective In this study, we aimed to analyze serum exosomal miR-216b expression in NSCLC patients a
Publikováno v:
Cancer biomarkers : section A of Disease markers. 26(3)
BACKGROUND Lung squamous cell carcinoma (LUSC) is malignant disease with poor therapeutic response and unfavourable prognosis. OBJECTIVE This study aims to develop a long non-coding RNA (lncRNA) signature for survival prediction in patients with LUSC
Publikováno v:
Cancer biomarkers : section A of Disease markers. 25(3)
Background The expression of neuropilin-1 (NRP-1) in Epstein-Barr virus (EBV)-associated lymphomas and its relationships with clinicopathological parameters was investigated. Methods The researchers compared 111 cases of patients with lymphoma to 20
Publikováno v:
Cancer biomarkers : section A of Disease markers. 25(3)
Background There were no specific indicators for the early detection of pancreatic cancer. Objective To analyze the diagnostic and prognostic value of CA19-9 plus B7-H4 detection in preoperative serum or surgical tissues of patients with pancreatic c
Publikováno v:
Cancer biomarkers : section A of Disease markers. 25(2)
Background Laryngeal squamous cell carcinoma (LSCC) constitutes the third most frequent head and neck cancer. Several tissue biomarkers have been studied for their prognostic significance in LSCC. Objective To investigate the prognostic significance
Publikováno v:
Cancer biomarkers : section A of Disease markers. 25(2)
BACKGROUND The microRNA plays an important role in tumor progression. MiR-1236-3p acts as a tumor suppressor in various malignancies. OBJECTIVE The aim of present study was to explore the expression of miR-1236-3p in gastric cancer (GC) and its corre
Autor:
Tae Sung Ahn, Seunghyun Oh, Seona Ban, Dongjun Jeong, Sanghee Ji, Moon Soo Lee, Dong Hyun Kang, Han Jo Kim, Hyun Yong Lee, Moo-Jun Baek, Doyeon Kim, Hyeongjoo Kim, Sang Byung Bae, Chang-Jin Kim, Hyog Young Kwon
Publikováno v:
Cancer biomarkers : section A of Disease markers. 24(4)
Defensin alpha 6 (DEFA6) is a member of the alpha defensin family of microbicidal and cytotoxic peptides that defend against bacteria and viruses. Here, we provide a novel function of DEFA6 in tumorigenesis of colorectal cancer (CRC) in vitro and in
Publikováno v:
Cancer biomarkers : section A of Disease markers. 24(4)
Background Long noncoding RNA have been indicated to be involved in tumor development. However, the role of LINC00460 in gastric cancer (GC) still remains large unknown. The current study is designed aiming at determining the effects of LINC00460 on