Zobrazeno 1 - 3
of 3
pro vyhledávání: '"David F. Claxton"'
Autor:
Hong Gang Wang, Christopher M. Dower, Kenichiro Doi, Qiang Liu, Shen Shu Sung, Krishne Gowda, David F. Claxton, Shantu Amin, Jyh Ming Lin, Thomas P. Loughran
Publikováno v:
Cancer Biology & Therapy. 15:1688-1699
Mcl-1, a pro-survival member of the Bcl-2 protein family, is an attractive target for cancer therapy. We have recently identified the natural product marinopyrrole A (maritoclax) as a novel small molecule Mcl-1 inhibitor. Here, we describe the struct
Autor:
Brian M. Barth, Thomas P. Loughran, Krishne Gowda, Shantu Amin, Qiang Liu, Hong Gang Wang, David F. Claxton, Kenichiro Doi
Publikováno v:
Cancer Biology & Therapy. 15:1077-1086
Acute myeloid leukemia (AML) is one of the deadliest leukemias for which there is an urgent and unmet need for the development of novel treatment strategies. Multiple drug resistance mechanisms mediate poor drug response and relapse in patients, and
Autor:
Sulfi Ibrahim, David F. Claxton
Publikováno v:
Cancer Biology & Therapy. 8:1101-1101
Commentary to:Utility of the systemic inflammatory response syndrome (SIRS) criteria in predicting the onset of septic shock in hospitalized patients with hematologic malignanciesAnthony Mato, Selina Luger, Daniel F. Heitjan, Rosemarie Mick, Scott D.