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Autor:
Angelo M. De Marzo, Andrew S. Goldstein, Michael A. Teitell, Matthew Rettig, Preston D. Crowell, Jack Mottahedeh, Tristan Grogan, David M. Esopi, Takao Hashimoto, William B. Isaacs, Michael C. Haffner, Elizabeth A. Platz, Himisha Beltran, Rohan Bareja, Srinivasan Yegnasubramanian, David Elashoff, Andrea Sboner
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-17 (2018)
Cancer & metabolism, vol 6, iss 1
Cancer & metabolism, vol 6, iss 1
Background Cancer cell metabolism requires sustained pools of intracellular nicotinamide adenine dinucleotide (NAD+) which is maintained by a balance of NAD+ hydrolase activity and NAD+ salvage activity. We recently reported that human prostate cance