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pro vyhledávání: ''
Autor:
Fiori Alite, Brian Bingham, Hanmanth J. Neboori, John M. Holland, Kyle Wang, Sameera S. Kumar, Weining Zhen, Salma K. Jabbour, Valerie Shostrom, Charles B. Simone, John M. Stahl, Christopher L. Hallemeier, Albert Attia, Matthew M. Harkenrider, Adrian S. Iskhanian, Percy Lee, Steve Braunstein, Roy H. Decker, Joshua M. Walker, Ronald C. McGarry, C. Hadzitheodorou, Vivek Verma
Publikováno v:
Cancer. 123:688-696
BACKGROUND Stereotactic body radiotherapy (SBRT) is the standard of care for patients with nonoperative, early-stage non–small cell lung cancer (NSCLC) measuring
Autor:
Jin Seok Ahn, Sook Jung Jo, Hong Suk Song, Sang-We Kim, Jong-Mu Sun, Myung-Ju Ahn, Keunchil Park, Yeul Hong Kim, Keehyun Lee, Hoon Kyo Kim, Dae Ho Lee, In Gyu Hwang, Hwan Jung Yun, Ki Hyeong Lee, Young Joo Min, Jae Won Lee, Bong-Seog Kim
Publikováno v:
Cancer. 118:6234-6242
BACKGROUND: Gefitinib was compared with pemetrexed as second-line therapy in a clinically selected population previously treated with platinum-based chemotherapy. METHODS: A phase 3 trial of gefitinib (250 mg/day) versus pemetrexed (500 mg/m2 on day
Publikováno v:
Cancer. 118:5572-5579
BACKGROUND: The current study characterizes the overall survival (OS) and cause-specific survival (CSS) of patients with stage I nonsmall cell lung cancer (NSCLC) who were treated with radiotherapy alone, and analyzes the variables potentially affect
Autor:
Steven J. Mentzer, Elizabeth H. Baldini, Megan Othus, David J. Sugarbaker, Aaron M. Allen, Bruce E. Johnson, Pasi A. Jänne, Michael S. Rabin, Hale B. Caglar, Raphael Bueno
Publikováno v:
Cancer. 115:4156-4166
BACKGROUND: The objective of this study was to identify the factors associated with improved outcome after treatment for stage III nonsmall cell lung cancer (NSCLC). METHODS: A retrospective review of stage III NSCLC patients treated at who were trea
Is sex associated with the outcome of patients treated with radiation for nonsmall cell lung cancer?
Autor:
James D. Cox, Joe Y. Chang, Ritsuko Komaki, Mary Frances McAleer, M. Kara Bucci, Michael S. O'Reilly, Melenda Jeter, Susan L. McGovern, Zhongxing Liao, Pamela K. Allen
Publikováno v:
Cancer. 115:3233-3242
BACKGROUND: Lung cancer is the leading cause of cancer death for both men and women, but the disease course differs between the sexes. To the authors' knowledge, sex-based differences in outcomes among the population of nonsmall cell lung cancer (NSC
Publikováno v:
Cancer. 112:2756-2764
BACKGROUND. The double-strand break (DSB) repair capacity has been implicated in the survival of patients in several cancer types. However, little is known about the prognostic importance of the key DSB repair genes—ataxia-telangiectasia mutated (A
Autor:
Se-Hoon Lee, Sun Ha Paek, Hyun-Tai Chung, Dae Hee Han, Dong Gyu Kim, Joohyun Kim, Hee-Won Jung, Seung-Yeob Yang
Publikováno v:
Cancer. 112:1780-1786
BACKGROUND The aim of the current study was to determine whether a pulmonary resection and gamma-knife radiosurgery (GKRS) protocol is superior to GKRS alone in selected patients with stage IV nonsmall-cell lung cancer (NSCLC). METHODS The authors pe
Autor:
Tomoyuki Goya, Hidefumi Takei, Yoshihiko Koshiishi, Takashi Watanabe, Masachika Fujiwara, Kouki Ohtsuka, Hiroaki Ohnishi, Satsuki Matsushima, Go Furuyashiki, Tomonori Kishino
Publikováno v:
Cancer. 109:741-750
BACKGROUND. Tyrosine kinase domain (TKD) gene mutations of the epidermal growth factor receptor gene (EGFR) have proven to be clinically significant in nonsmall-cell lung cancer (NSCLC), particularly in adenocarcinoma. However, TKD mutations together
Autor:
Charles R. Thomas, Frank C. Detterbeck, Ann M. Geiger, W. Jeffrey Petty, Timothy E. Oaks, Mitchell Machtay, Brian E. Lally, Lynn D. Wilson, A. William Blackstock, Antonius A. Miller, Mike E. Robbins
Publikováno v:
Cancer. 110:911-917
BACKGROUND. This study was designed to investigate whether the mortality from heart disease, a manifestation of intercurrent disease after postoperative radiotherapy (PORT), has decreased over time for patients with nonsmall cell lung cancer (NSCLC).
Autor:
Michele Milella, Alessandra Mirri, Anna Ceribelli, Alain Gelibter, Mauro Caterino, Maria Simona Pino, F.L. Cecere, Francesco Cognetti, Francesco Facciolo
Publikováno v:
Cancer. 109:727-731
BACKGROUND. Improving results in nonsmall-cell lung cancer (NSCLC) will require the development of new drugs and strategies to combine available agents. On the basis of data indicating the activity of docetaxel as second-line therapy, a Phase II stud