Zobrazeno 71 - 80
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Autor:
Shigeru Itabashi, Tamotsu Takishima, Kiyohisa Sekizawa, Hidetada Sasaki, Masatoshi Morikawa, Takashi Aikawa
Publikováno v:
British Journal of Pharmacology. 105:609-612
1. We investigated the role of adenosine 3':5'-cyclic monophosphate (cyclic AMP) in non-adrenergic non-cholinergic (NANC) contraction in guinea-pig bronchial strips. 2. Forskolin (3 nM to 1 microM) reduced NANC contraction induced by electrical field
Publikováno v:
British Journal of Pharmacology. 105:516-520
1. The effect of adenosine triphosphate (ATP) and its stable analogues, alpha, beta-methylene-ATP and beta, gamma-methylene-ATP, on the efferent function of capsaicin-sensitive non-adrenergic, non-cholinergic (NANC) nerves was tested in guinea-pig is
Autor:
Gavin J. Kilpatrick, S.J. Taylor
Publikováno v:
British Journal of Pharmacology. 105:667-674
1. In the presence of atropine, mepyramine and ranitidine, electric field stimulation of the guinea-pig isolated ileum longitudinal muscle-myenteric plexus preparation resulted in a two component non-adrenergic non-cholinergic contraction. The initia
Publikováno v:
British Journal of Pharmacology. 105:347-354
1. The roles of autofeedback and neuronal uptake in neurotransmission produced by electrical field stimulation in several rabbit isolated blood vessels were examined. 2. Blocking drugs were used to separate the possible purinergic and noradrenergic c
Autor:
Jane E. Nally, T.C. Muir
Publikováno v:
British Journal of Pharmacology. 105:367-375
1. Electrical and mechanical responses to field stimulation (1-64 Hz, 0.5 ms supramaximal voltage) were recorded simultaneously in the rabbit saphenous artery. The electrical response consisted entirely of excitatory junction potentials (e.j.ps) whic
Autor:
Keiko Suzuki, Tadashi Takewaki, Kaoru Masuzawa-Ito, Katsuaki Ito, Masahisa Asano, Hikaru Suzuki, Tomohiro Kanno, Hidenori Ohashi
Publikováno v:
British Journal of Pharmacology. 105:335-340
1. The effects of cromakalim on mechanical and electrical activities of the circular smooth muscles of guinea-pig stomach antrum were observed. 2. Cromakalim (greater than 1 x 10(-7) M) decreased the amplitude of spontaneous rhythmic contractions and
Publikováno v:
British Journal of Pharmacology. 105:393-399
1 To examine the role of epithelium in the responsiveness of tracheal smooth muscle in rabbit, we measured the contractile responses to acetylcholine (ACh), KCl, 5-hydroxytryptamine (5-HT), histamine, substance P (SP), neurokinin A (NKA), and electri
Publikováno v:
British Journal of Pharmacology. 105:113-118
1. The effects of vesamicol, an inhibitor of vesicular acetylcholine (ACh) storage, were studied on trains of endplate currents (e.p.cs) in the cut rat hemidiaphragm nerve-muscle preparation and on trains of focally recorded nerve terminal current wa
Autor:
Pèteris Alberts
Publikováno v:
British Journal of Pharmacology. 105:142-146
1. The following experiments were carried out to investigate the presence and type of functional presynaptic receptors in adrenergic nerves of the guinea-pig urethra. 2. The urethra from male guinea-pigs was incubated with [3H]-noradrenaline and supe
Publikováno v:
British Journal of Pharmacology. 104:928-932
1. This study investigated the responsiveness to vasoconstrictor agents (including endothelin-1, ET-1) of aortic rings from rats with two-week streptozotocin (STZ, 60 mg kg-1, i.v.)-induced diabetes and vehicle-treated control rats. The basal tension