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Autor:
Daniele Del Rio, Guillaume Gautheron, Jean-François Guichou, Gérard Cros, Catherine Oiry, Richard Magous, Morgane Bayle, Estelle Youl, Jérémie Neasta, Jean-François Quignard, Alan Crozier, Anne Virsolvy, Margherita Dall'Asta
Publikováno v:
Br J Pharmacol
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2019, ⟨10.1111/bph.14821⟩
British Journal of Pharmacology, 2019, ⟨10.1111/bph.14821⟩
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2019, ⟨10.1111/bph.14821⟩
British Journal of Pharmacology, 2019, ⟨10.1111/bph.14821⟩
BACKGROUND AND PURPOSE: The pharmacology of polyphenol metabolites on beta‐cell function is largely undetermined. We sought to identify polyphenol metabolites that enhance the insulin‐secreting function of beta‐cells and to explore the underlyi
Publikováno v:
British Journal of Pharmacology. 157:944-951
Background and purpose: Sodium sulphide (Na2S) disassociates to sodium (Na+) hydrosulphide, anion (HS-) and hydrogen sulphide (H2S) in aqueous solutions. Here we have established and characterized a method to detect H2S gas in the exhaled breath of r
Autor:
G.L. Raymond, I.R. Wendt
Publikováno v:
British Journal of Pharmacology. 119:1029-1037
1. Simultaneous recordings of tension and [Ca2+]i were made in rat anococcygeus muscle strips to investigate possible mechanisms involved during cyclic nucleotide-mediated relaxation. Relaxation of pre-contracted muscles was induced by sodium nitropr
Publikováno v:
British Journal of Pharmacology. 118:1772-1778
1. Whole cell recordings of voltage-activated K+ currents were made with the amphotericin B perforated patch technique from cerebellar granule (CG) neurones of 6-8 days rats that had been in culture for 1 to 16 days. By use of appropriate voltage pro
Autor:
Minoru Watanabe, Masahisa Asano, Yuji Imaizumi, Yoshiaki Uyama, Yukiko Nomura, Kaoru M. Ito, Katuaki Ito, Miho Kuwako
Publikováno v:
British Journal of Pharmacology. 118:1019-1027
1. The Ca2+ buffering function of sarcoplasmic reticulum (SR) in the resting state of arteries from spontaneously hypertensive rats (SHR) was examined. Differences in the effects of ryanodine that removes the function of SR, on tension and cellular C
Publikováno v:
British Journal of Pharmacology. 117:1549-1557
1. The vasodilator properties and photochemical decomposition of two synthetic iron-sulphur-nitrosyl clusters (cluster A: [Fe4S4(NO)4], tetranitrosyl-tetra-mu 3-sulphido-tetrahedro-tetrairon; and B:[Fe4S3 (NO)7]-1, heptanitrosyl-tri-mu 3-thioxotetraf
Publikováno v:
British Journal of Pharmacology. 116:2468-2472
1. Besipirdine (HP 749) is a compound undergoing clinical trials for efficacy in treating Alzheimer's disease. Among other pharmacological effects, besipirdine inhibits voltage-dependent sodium and potassium channels. This paper presents a pharmacolo
Autor:
M. Teresa Miras-Portugal, Jesús Pintor
Publikováno v:
British Journal of Pharmacology. 115:895-902
1. Diadenosine polyphosphates, Ap4A and Ap5A, as well as ATP, alpha,beta-MeATP and ADP-beta-S, were able to elicit variable intrasynaptosomal Ca2+ increases in rat midbrain synaptic terminals. The origin of the Ca2+ increment was the extra synaptosom
Publikováno v:
British Journal of Pharmacology. 114:1165-1170
1. The effects of depletion of intracellular Ca2+ stores on muscle tension and the intracellular Ca2+ concentration ([Ca2+])i were studied in fura-2 loaded longitudinal smooth muscle cells of the rat ileum. 2. After exposure to a Ca(2+)-free solution
Publikováno v:
British Journal of Pharmacology. 112:360-368
1. We have examined the effects of nitric oxide inhibition, indomethacin and the dual lipoxygenase/cyclo-oxygenase inhibitor, 3-amino-1-[m-(trifluoromethyl)-phenyl]-2-pyrazoline (BW755C), on the responses of small mesenteric arteries of Wistar rats,