Zobrazeno 41 - 50
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Autor:
Renato S.B. Cordeiro, Patrícia M.R. e Silva, Christianne Bandeira-Melo, Yajaira Singh, Marco A. Martins
Publikováno v:
British Journal of Pharmacology. 118:2192-2198
1. Recent evidence has implicated eosinophils in the inhibition of allergen-induced rat pleurisy, but the mechanism of this negative modulation is not completely understood. This study was undertaken in order to define the potential role of prostagla
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
1. The effects of the selective and potent novel platelet-activating factor (PAF) antagonist, UR-12633 (1-(3,3-diphenylpropionyl)-4-(3-pyridylcyanomethyl)piperidin e) on several markers of endotoxic shock syndrome were evaluated in rats and mice. 2.
Autor:
C. M. Herd, Mark Holbrook, A. Z. El-Hashim, Clive P. Page, S.M. Blake, Gerry Higgs, Neil Gozzard, B. Hughes
Publikováno v:
British Journal of Pharmacology. 118:1201-1208
1. The effects of the inhaled corticosteroid budesonide and a novel PDE 4 inhibitor CDP840 given systematically, were evaluated in a model of antigen-induced airway inflammation in the rabbit. 2. Adult litter-matched NZW rabbits (2.4-3.5 kg) immunise
Publikováno v:
British Journal of Pharmacology. 118:893-900
1. The effects of the calcium channel blockers, verapamil and nifedipine on myocardial ischaemia and oedema evoked by endothelin-1 (ET-1) or IRL 1620, an ETB receptor-selective agonist were studied in anaesthetized and conscious rats. 2. Bolus inject
Autor:
Karl B. Thor, Hansjörg Danuser
Publikováno v:
British Journal of Pharmacology. 118:150-154
1. 5-Hydroxytryptamine (5-HT) is intimately associated with central sympathetic and somatic control of the lower urinary tract. The sympathetic and somatic innervation of the lower urinary tract is conveyed through efferent axons of the hypogastric a
Publikováno v:
British Journal of Pharmacology. 117:1685-1692
1. Monophosphoryl lipid A (MLA) is a non-pyrogenic derivative of Salmonella lipopolysaccharide. Administration of this agent at high doses to rats and at low doses to dogs was previously shown to confer marked protection against ischaemia-reperfusion
Autor:
Vera Lucia Gonçalves de Moraes, Jean Lefort, B. Boris Vargaftig, Michel Chignard, Anthony Meager
Publikováno v:
British Journal of Pharmacology. 117:1792-1796
1. The adult respiratory distress syndrome (ARDS) is an acute lung inflammation developed after direct or indirect contact with pathogenic agents. In the present study, a mouse model was developed to mimic this condition using aerosolized bacterial l
Publikováno v:
British Journal of Pharmacology. 117:1047-1052
1. The aim of this study was to investigate whether global ischaemia and reperfusion in rat isolated hearts affects endothelium-dependent vasodilatation and adrenoceptor-mediated vasoconstriction. In addition, it was first determined whether inhibiti
Autor:
Takio Ohka, Kouichi Nishi, Masayuki Mizuguchi, Tokunao Amemiya, Tamotsu Matsuda, Masaki Fujimura
Publikováno v:
British Journal of Pharmacology. 117:443-448
1. In this study, the role of neuropeptides in antigen-induced bronchoconstriction and bronchial responsiveness in guinea-pigs was evaluated by use of phosphoramidon, the inhibitor of neutral endopeptidases (NEP), the NK1 receptor antagonist, FK888,
Autor:
Jesús Angulo, P Cuevas, Rocío González-Corrochano, Argentina Fernández, MX Chen, JM La Fuente, I. Saenz de Tejada
Publikováno v:
British journal of pharmacology. 169(2)
Background and Purpose We have evaluated the influence of calcium-activated potassium channels (KCa) activation on cGMP-mediated relaxation in human penile tissues from non-diabetic and diabetic patients, and on the effects of PDE5 inhibitors on erec