Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ghigo, A."'
Autor:
Ignacio-Andres Romero, P.O. Couraud, Chiara Riganti, Ruth Garzón, Dario Antonio Ghigo, Martha L. Pinzon-Daza, Babette B. Weksler, Amalia Bosia
Publikováno v:
British Journal of Pharmacology. 167:1431-1447
BACKGROUND AND PURPOSE The passage of drugs across the blood–brain barrier (BBB) limits the efficacy of chemotherapy in brain tumours. For instance, the anticancer drug doxorubicin, which is effective against glioblastoma in vitro, has poor efficac
Publikováno v:
British Journal of Pharmacology. 158:1777-1786
Background and purpose: Statins, inhibitors of hydroxymethylglutaryl-CoA reductase, reduce the intracellular synthesis of cholesterol and prevent the onset of atherosclerosis. They also decrease the synthesis of isoprenoid molecules, such as the side
Autor:
Sophie Doublier, Chiara Riganti, Dario Ghigo, Daniele Viarisio, Gianpiero Pescarmona, Erica Miraglia, Amalia Bosia
Publikováno v:
British Journal of Pharmacology. 156:1054-1066
Background and purpose Artemisinin is an antimalarial drug exerting pleiotropic effects, such as the inhibition of the transcription factor nuclear factor-kappa B and of the sarcoplasmic/endoplasmic reticulum Ca(++)-ATPase (SERCA) of P. falciparum. A