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Autor:
Takaji Matsutani, Eiichi Ohtsuka, Yoshitaka Imaizumi, Kenji Ishitsuka, Asahi Ito, Makoto Yoshimitsu, Kentaro Yonekura, Ilseung Choi, Atae Utsunomiya, Kisato Nosaka, Nobuaki Nakano, Shinsuke Iida, Ryuzo Ueda, Michihiro Hidaka, Toshiro Kawakita, Takashi Ishida, Youko Suehiro, Junya Makiyama, Hiro Tatetsu, Hidenori Sasaki, Shigeru Kusumoto, Takeharu Kato, Tatsuro Jo, Masao Ogata
Publikováno v:
British Journal of Haematology. 196:629-638
'Monitoring of immune responses following mogamulizumab-containing treatment in patients with adult T-cell leukaemia-lymphoma (ATL)' (MIMOGA) is a multicentre prospective clinical study (UMIN000008696). In the MIMOGA study, we found that a lower perc
Autor:
James B. Bussel, Quentin A. Hill, Michelle Sholzberg, Nichola Cooper, Michael D. Tarantino, Sandra Tong, Leslie Todd, Ralph V. Boccia, Michael Boxer, Waleed Ghanima
Publikováno v:
British Journal of Haematology
Fostamatinib demonstrated efficacy in phase 3 trials of adults with immune thrombocytopenia (ITP). Post hoc analysis compared patients who received fostamatinib as second‐line therapy (after steroids ± immunoglobulins) versus third‐or‐later‐
Autor:
Jesus Feliu, Mercedes Rodríguez-Calvillo, Ricardo García-Muñoz, Pilar Giraldo, Ángel Panizo, Susana Inogés, Jorge M. Núñez-Córdoba, Eva Bandrés, Ascensión López-Díaz de Cerio, Nicolas Martinez-Calle, Marcio Andrade-Campos, Esther Pena, Carlos Panizo, Carlos Grande, María Teresa Olave
Publikováno v:
British Journal of Haematology. 189:1064-1073
Anti-cluster of differentiation 20 (CD20) monoclonal antibodies (mAbs) have shown promise in follicular lymphoma (FL) as post-induction therapy, by enhancing antibody-dependent cellular cytotoxicity (ADCC). However, cytotoxic cells are reduced after
Autor:
Georg Aue, Robert Reger, Phuong Vo, Richard W. Childs, Tatyana Worthy, Sharon Adams, Willy A. Flegel, Brian Wells, Emily C. McDuffee, Xin Tian, Kamille A. West, Reem Shalabi, Enkhtsetseg Purev, Geri Hawks, Lisa Cook
Publikováno v:
Br J Haematol
Heavily transfused patients frequently develop human leukocyte antigen (HLA) allo-immunization resulting in platelet transfusion refractoriness and a high risk for life-threatening thrombocytopenia. Data suggest complement activation leading to the d
Autor:
Tom van Meerten, Lydia Visser, Marcel Nijland, Andor W. J. M. Glaudemans, Arjan Diepstra, Anke van den Berg, Hanneke C. Kluin-Nelemans, Gustaaf W. van Imhoff, Wouter J. Plattel
Publikováno v:
British Journal of Haematology
British Journal of Haematology, 190(1), 40-44. Wiley
British Journal of Haematology, 190(1), 40-44. Wiley
Serum thymus and activation regulated chemokine (TARC) levels reflect classical Hodgkin lymphoma (cHL) disease activity and correspond with treatment response. We compared mid-treatment interim TARC (iTARC) with interim 18 F-fluorodeoxyglucose positr
Autor:
Kloos, Robin, van der Sluis, Inge M, Mastrobattista, Enrico, Hennink, Wim, Pieters, Rob, Verhoef, Jan-Jaap, Afd Pharmaceutics, Pharmaceutics
Publikováno v:
British Journal of Haematology, 189(3), 442. Wiley-Blackwell
British Journal of Haematology, 189(3), 442-451. Wiley-Blackwell Publishing Ltd
British Journal of Haematology, 189(3), 442-451. Wiley-Blackwell Publishing Ltd
Polyethylene glycol (PEG) conjugated asparaginase (PEGasparaginase) is essential for treatment of paediatric acute lymphoblastic leukaemia. We developed an assay identifying antibodies against the PEG-moiety, the linker and the drug itself in patient
Autor:
Daniel Aeberli, Axel Finckh, Peter M. Villiger, Martin Fiedler, Almut Scherer, Burkhard Möller, Godehard Scholz, Uta Arndt, Cem Gabay, Diego Kyburz, Alexander Benedikt Leichtle
Publikováno v:
British Journal of Haematology, Vol. 186, No 1 (2019) pp. 101-112
Anaemia affects quality of life and radiographic outcome in rheumatoid arthritis (RA). In a cross-sectional study with 779 patients, we assessed the prognostic potential of the major haematopoietic regulators, hepcidin and erythropoietin, comparing t
Autor:
Wilma Barcellini, Juri Alessandro Giannotta, Anna Paola Marcello, Elisa Fermo, Cristina Vercellati, Paola Bianchi, Maria Domenica Cappellini, Lorena Duca, Giulia Soverini, Patrizia Pedrotti, Anna Zaninoni, Anna Ines Gregorini, Bruno Fattizzo
Publikováno v:
British Journal of Haematology. 185:523-531
Iron overload (IO) is poorly investigated in the congenital haemolytic anaemias (CHAs), a heterogeneous group of rare inherited diseases encompassing abnormalities of the erythrocyte membrane and metabolism, and defects of the erythropoiesis. In this
Autor:
Craig Tendler, Mary Guilfoyle, Frits van Rhee, David C. Fajgenbaum, Dustin Shilling, Sepideh Nemat, Carlos Appiani, Deanna E Morra, Sheila K Pierson
Publikováno v:
Br J Haematol
Siltuximab is the only US Food and Drug Administration-approved treatment for idiopathic multicentric Castleman disease (iMCD), a rare haematological disorder associated with substantial morbidity and mortality. Although siltuximab induces a response
Publikováno v:
British Journal of Haematology
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