Zobrazeno 1 - 10
of 20
pro vyhledávání: '"64"'
Publikováno v:
British Journal of Haematology. 110:223-227
Anti-HPA-5b is the most commonly found platelet-specific antibody among pregnant women, but it does not cause severe fetal-neonatal alloimmune thrombocytopenia in the majority of affected infants. However, as the sequelae of the affected children may
Autor:
Peter D. Issitt, J. A. Tessel, C. A. Bell, H. Zwicker, S. W. Kroovand, B. G. Pavone, C. H. Issitt, D. Goldfinger
Publikováno v:
British Journal of Haematology. 34:5-17
SUMMARY Eluates from the red blood cells (and sera whenever free autoantibody was present) of 150 individuals with positive direct antiglobulin tests, have been studied for antibody specificity. Of 87 patients with AIHA, 64 had autoantibodies reactin
Autor:
Ayalew Tefferi, Ketterling Rhett, Animesh Pardanani, Terra L. Lasho, Emnet A. Wassie, Curtis A. Hanson, Christy Finke, Naseema Gangat
Publikováno v:
British Journal of Haematology. 169:71-76
Background : Recent studies have suggested significant associations between karyotype and certain molecular or phenotypic features in primary myelofibrosis (PMF). In the current study of 835 consecutive patients, we examined the spectrum and prevalen
Publikováno v:
British Journal of Haematology. 165:842-853
Summary To assess sources of variability in platelet function tests in normal subjects, 64 healthy young adults were tested on 2–6 occasions at 2 week intervals using four methods: platelet aggregation (AGG) in platelet-rich plasma (PRP) in the Bio
Autor:
Susanna Barella, Simona Campus, Raffaella Origa, Renzo Galanello, Patrizio Bina, Maria Carla Sollaino, L Perseu, C. Mandas, Nicolina Giagu
Publikováno v:
British Journal of Haematology. 136:326-332
In this study, 251 Sardinian patients (187 adults and 64 children) with haemoglobin (Hb) H disease were evaluated. Two-hundred and sixteen patients (86%) had the deletional type (- -/-alpha) and 36 (14%) patients had the non-deletional type (- -/alph
Autor:
Annette Schmitt-Gräff, Jochen Wilpert, Gerd Walz, Johannes Donauer, Thomas Maiwald, Heike L. Pahl, Titus Sparna, Philipp S. Goerttler, Jens Timmer, Clemens Kreutz, Brigitta Rumberger, Daniel Faller, Edith März
Publikováno v:
British Journal of Haematology. 129:138-150
Summary The molecular aetiology of polycythaemia vera (PV) remains unknown and the differential diagnosis between PV and secondary erythrocytosis (SE) can be challenging. Gene expression profiling can identify candidates involved in the pathophysiolo
Autor:
Céline Pangault, Renée Fauchet, Marc Bernard, Bernard Drenou, Thierry Lamy, Laurence Amiot, Jean-Marc Grosset, Gaëlle Le Friec
Publikováno v:
British Journal of Haematology. 119:417-424
Summary. An optimal antitumoral immune response requires the participation of both CD8 and CD4 T lymphocytes, which are activated by peptide antigen presentation via human leucocyte antigen (HLA) class I and class II molecules respectively. Loss of H
Autor:
Eiichi Ishii, Toshihiko Imamura, Shigeyoshi Hibi, Mami Takanashi, Shinsaku Imashuku, Yasuhiro Tabata, Tomohito Yagi, Akira Morimoto
Publikováno v:
British Journal of Haematology. 117:525-530
The Ikaros (Ik) gene family, which includes Ik, Aiolos (Ai), and Helios (He), is a primary regulator of lymphocyte differentiation, and is involved in the development of acute lymphoblastic leukaemia (ALL). We analysed the expression of the Ik gene f
Autor:
Hiroshi Miyazaki, Kousaku Matsubara, Hidekazu Harigaya, Takashi Kato, Kunizo Baba, Hiroyuki Nigami, Akira Ishiguro
Publikováno v:
British Journal of Haematology. 115:963-968
To verify pathophysiological mechanisms underlying thrombocytosis in low-birth-weight (LBW) preterm babies, we evaluated kinetic changes in platelet counts and thrombopoietic cytokines including thrombopoietin (TPO), interleukin 6 (IL-6) and IL-11 in
Publikováno v:
British Journal of Haematology. 114:70-77
Flavopiridol, a synthetic flavone, is currently under clinical investigation for the treatment of B-cell chronic lymphocytic leukaemia (B-CLL). In this study, we examined the in vitro effects of flavopiridol and fludarabine on B-CLL cells from 64 pat