Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Hydrocortisone"'
Autor:
Al‐Kofahi, Mahmoud1 (AUTHOR) malkofah@umn.edu, Ahmed, Mariam A.1,2 (AUTHOR), Jaber, Mutaz M.1 (AUTHOR), Tran, Thang N.1 (AUTHOR), Willis, Brian A.3 (AUTHOR), Zimmerman, Cheryl L.1 (AUTHOR), Gonzalez‐Bolanos, Maria T.4 (AUTHOR), Brundage, Richard C.1 (AUTHOR), Sarafoglou, Kyriakie1,4 (AUTHOR)
Publikováno v:
British Journal of Clinical Pharmacology. Mar2021, Vol. 87 Issue 3, p1098-1110. 13p.
Autor:
Neil Barnes, Tim Harrison, Daren Austin, Dave Singh, Sebin Thomas, Noushin Brealey, Peter T. Daley-Yates, Shaila S. Shabbir
Publikováno v:
British journal of clinical pharmacology. 87(2)
Aims To compare the airway potency, systemic activity and therapeutic index of three inhaled corticosteroids that differ in glucocorticoid receptor binding affinity, physicochemical and pharmacokinetic properties. Methods This escalating-dose, placeb
Autor:
Brian A. Willis, Mariam A. Ahmed, Thang N. Tran, Richard C. Brundage, Maria Teresa Gonzalez-Bolanos, Kyriakie Sarafoglou, Mahmoud Al-Kofahi, Mutaz M. Jaber, Cheryl L. Zimmerman
Publikováno v:
British journal of clinical pharmacology. 87(3)
Aims The aim of this study was to characterize the pharmacokinetic/pharmacodynamic relationships of cortisol and the adrenal biomarkers 17-hydroxyprogesterone and androstenedione in children with congenital adrenal hyperplasia (CAH). Methods A nonlin
Autor:
Riccardo Volpi, Paolo Chiodera, Elio Volta, M. L. Maffei, Adriano Stella, A. Casti, Vittorio Coiro
Publikováno v:
British Journal of Clinical Pharmacology. 71:951-955
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Alprazolam (ALP), a benzodiazepine activating GABAergic receptors, is involved in ACTH secretion. WHAT THIS STUDY ADDS • This study demonstrates a partial opioid influence in the inhibitory effect of ALP
Autor:
Chay Ngee Lim, Stephen D. Wiss, Christopher Chen, Sitra Tauscher-Wisniewski, Louise Mooney, Stephen L. Lowe, Gordon B. Cutler, Guan Koon Ong, Brian A. Willis
Publikováno v:
British Journal of Clinical Pharmacology. 70:886-894
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • The insulin tolerance test (ITT) is commonly used to induce cortisol release in response to physiological stress. This methodology can be employed in studies evaluating the hypothalamic-pituitary-adrenocor
Autor:
Renske S A Kramer, Frank H J van den Hoogen, A.M.M. Eijsbouts, Fred C.G.J. Sweep, Ad R. M. M. Hermus, Maria T. E. Hopman, Marlies Kempers, Leo B A van de Putte, Ronald F J M Laan
Publikováno v:
British Journal of Clinical Pharmacology, 67, 1, pp. 22-8
British Journal of Clinical Pharmacology, 67, 22-8
British Journal of Clinical Pharmacology, 67, 22-8
Contains fulltext : 80852.pdf (Publisher’s version ) (Closed access) AIM: To study the effect of the nonsteroidal anti-inflammatory drug naproxen on the activity of the hypothalamic-pituitary-adrenal (HPA) axis in healthy volunteers. METHODS: A dou
Publikováno v:
British Journal of Clinical Pharmacology. 64:125-132
What is already known about this subject • The functionality of the HPA axis through cortisol production has been the subject for several investigations. • Modelling of cortisol production has been described by endogenous substance models utilizi
Autor:
V. Corbrion Archer, D. Warot, O. Chosidow, Bertrand Diquet, Alain J. Puech, Jean-Claude Levron, Bénédicte Lebrun-Vignes
Publikováno v:
British Journal of Clinical Pharmacology. 51:443-450
Aims Itraconazole is a potent inhibitor of CYP3A4 activity and is often used in combination with corticosteroids. Since the latter are partly metabolized by CYP3A4, we studied the interaction between itraconazole, prednisone and methylprednisolone in
Autor:
Brian J. Lipworth, Adam Wilson
Publikováno v:
British Journal of Clinical Pharmacology. 48:579-585
Aims To determine the systemic dose–response relationships with oral prednisolone and inhaled fluticasone propionate administered in a putative 11:1 mg equivalent basis, in terms of effects on adrenal, bone and haematological markers.
Autor:
Hiroyoshi Nakamura, Shin-ichi Yamagata, Atsushi Hasegawa, Hisao Osada, Souei Sekiya, Hiromitsu Nakasa, Shigeru Ohmori, Mitsukazu Kitada, Maharu Kimura
Publikováno v:
British Journal of Clinical Pharmacology. 47:31-34
Aims To assess CYP3A enzyme activity in human neonates by measuring the urinary 6β-hydroxycortisol/cortisol (6β-OHF/C) ratio. Methods Fifty-six mature male neonates with normal delivery, seventeen of their mothers and twenty-four healthy non-pregna