Zobrazeno 1 - 10
of 504
pro vyhledávání: ''
Autor:
Laura E. Fischer, Sebastian Stintzing, Ludwig Fischer von Weikersthal, Dominik P. Modest, Thomas Decker, Alexander Kiani, Florian Kaiser, Salah-Eddin Al-Batran, Tobias Heintges, Christian Lerchenmüller, Christoph Kahl, Gernot Seipelt, Frank Kullmann, Martina Stauch, Werner Scheithauer, Clemens Giessen-Jung, Jens Uhlig, Bettina Peuser, Claudio Denzlinger, Arndt Stahler, Lena Weiss, Kathrin Heinrich, Swantje Held, Andreas Jung, Thomas Kirchner, Volker Heinemann
Publikováno v:
British Journal of Cancer. 127:836-843
Summary Background The evidence on the efficacy of anticancer therapy is limited in older patients with metastatic colorectal cancer (mCRC). This retrospective analysis of phase III FIRE-3 trial assesses the efficacy of FOLFIRI plus either cetuximab
Autor:
David Groshar, Jennifer Y. Wo, Motaz Qadan, Krista E Suarez-Weiss, James C. Cusack, Heike E. Daldrup-Link, Ricciardi Rocco, Amirkasra Mojtahed, Robin Striar, Liliana Bordeianou, Lale Umutlu, Felipe S. Furtado, Mark Anderson, Mark Vangel, Onofrio A. Catalano, Cristina R. Ferrone, Lawrence S. Blaszkowsky, Theodore S. Hong, Jeffrey W. Clark
Publikováno v:
Br J Cancer
Background Oligometastatic colorectal cancer (CRC) is potentially curable and demands individualised strategies. Methods This single-centre retrospective study investigated if positron emission tomography (PET)/magnetic resonance imaging (MR) had a c
Publikováno v:
Br J Cancer
Background Microwave ablation (MWA) is an effective minimally invasive technique for lung tumours. We aim to evaluate its role for pulmonary oligorecurrence after radical surgery of non-small-cell lung cancer (NSCLC). Methods From June 2012 to Jan 20
Autor:
Marko Bergovec, Andreas Leithner, Mark Goda, Maria Anna Smolle, Laurin Herbsthofer, Susanne Scheipl, Amin El-Heliebi, Martina Tomberger, Christopher Rossmann, Martin Pichler, Pablo López-García, Bernadette Liegl-Atzwanger, Barbara Prietl, Barbara Granegger, Armin Gerger, Joanna Szkandera, Jakob M. Riedl, Iva Brcic
Publikováno v:
Br J Cancer
BACKGROUND: Soft tissue sarcomas (STS) are generally considered non-immunogenic, although specific subtypes respond to immunotherapy. Antitumour response within the tumour microenvironment relies on a balance between inhibitory and activating signals
Autor:
Michele Ciccarelli, Nicolò Gennaro, Alexia Bertuzzi, Marco Alloisio, Armando Santoro, Umberto Cariboni, Laura Giordano, Andrea Dipasquale, Vittorio Quagliuolo, Andrea Marrari
Publikováno v:
British Journal of Cancer
Background The impact of active cancer in COVID-19 patients is poorly defined; however, most studies showed a poorer outcome in cancer patients compared to the general population. Methods We analysed clinical data from 557 consecutive COVID-19 patien
Autor:
Soong June Bae, Dooreh Kim, Junghwan Ji, Su Jung Baik, Sung Gwe Ahn, Joon Jeong, Sung Min Ko, Janghee Lee
Publikováno v:
British Journal of Cancer
Background Our study evaluated the association between body mass index (BMI) and absolute lymphocyte count (ALC) in breast cancer patients and healthy females. Additionally, we determined the prognostic value of these factors in breast cancer. Method
Autor:
Luigi Pedone Anchora, Valerio Gallotta, Francesco Fanfani, Camilla Fedele, Nicolò Bizzarri, Giacomo Avesani, Benedetta Gui, Vittoria Carbone, Giovanni Scambia, Matteo Bruno, Gian Franco Zannoni, Vito Chiantera, Anna Fagotti, Gabriella Ferrandina
Publikováno v:
Br J Cancer
Background: The aim of the present study was to assess the prognostic value of tumour-free distance (TFD), defined as the minimum distance of uninvolved stroma between the tumour and peri-cervical stromal ring, in early-stage cervical cancer. Methods
Autor:
Wei Mu, Matthew B. Schabath, Kenneth L. Gage, Evangelia Katsoulakis, Robert J. Gillies, Christopher J. Whelan
Publikováno v:
Br J Cancer
BACKGROUND: Approximately 50% of cancer patients eventually develop a syndrome of prolonged weight loss (cachexia), which may contribute to primary resistance to immune checkpoint inhibitors (ICI). This study utilised radiomics analysis of (18)F-FDG-
Autor:
Vincent Cheung, Rosalin Cooper, Isar Nassiri, Anna Olsson-Brown, Robert A. Watson, Mark Coles, Umair Akbani, Mark R. Middleton, Chelsea A Taylor, Joseph J. Sacco, Weiyu Ye, Oliver Brain, Rubeta N Matin, Robert D Morgan, Miranda Payne, Benjamin P. Fairfax, Nicholas Coupe
Publikováno v:
British Journal of Cancer
BRITISH JOURNAL OF CANCER
BRITISH JOURNAL OF CANCER
Background Immune checkpoint blockers (ICBs) activate CD8+ T cells, eliciting both anti-cancer activity and immune-related adverse events (irAEs). The relationship of irAEs with baseline parameters and clinical outcome is unclear. Methods Retrospecti
Autor:
Yesim Gökmen-Polar, Chrystal Chadwick, Fiona Ginty, Sunil Badve, Sanghee Cho, Anup Sood, Puay Hoon Tan, Adrian L. Harris, M Taylor, Elizabeth McDonough, Maria I. Zavodszky, Yunxia Sui, Michael J. Gerdes
Publikováno v:
British Journal of Cancer
Background There is limited knowledge about DCIS cellular composition and relationship with breast cancer events (BCE). Methods Immunofluorescence multiplexing (MxIF) was used to image and quantify 32 cellular biomarkers in FFPE DCIS tissue microarra