Zobrazeno 1 - 10
of 215
pro vyhledávání: ''
Publikováno v:
British Journal of Cancer
Background Markers of stromal activation at future metastatic sites may have prognostic value and may allow clinicians to identify and abolish the pre-metastatic niche to prevent metastasis. In this study, we evaluate tenascin-C as a marker of pre-me
Autor:
Saisai Wang, Dong Chen, Zhou Tong, Yongfeng Ding, Lulu Liu, Ruyi Zhang, Min Zhang, Xuanwen Bao, Weijia Fang, Peng Zhao, Hangyu Zhang, Xiaolin Li, Xiaohu Zhou, Yi Zheng, Benfeng Li, Jian Ruan, Xiaofei Cheng
Publikováno v:
Br J Cancer
BACKGROUND: Colorectal neuroendocrine carcinomas (CRNECs) are highly aggressive tumours with poor prognosis and low incidence. To date, the genomic landscape and molecular pathway alterations have not been elucidated. METHODS: Tissue sections and cli
Autor:
David Sefrioui, Ludivine Beaussire, André Gillibert, France Blanchard, Emmanuel Toure, Céline Bazille, Anne Perdrix, Frédéric Ziegler, Alice Gangloff, Mélanie Hassine, Caroline Elie, Anne-Laure Bignon, Aurélie Parzy, Philippe Gomez, Caroline Thill, Florian Clatot, Jean-Christophe Sabourin, Thierry Frebourg, Jacques Benichou, Karine Bouhier-Leporrier, Marie-Pierre Gallais, Nasrin Sarafan-Vasseur, Pierre Michel, Frédéric Di Fiore
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2021, ⟨10.1038/s41416-021-01431-9⟩
Br J Cancer
British Journal of Cancer, Cancer Research UK, 2021, ⟨10.1038/s41416-021-01431-9⟩
Br J Cancer
BACKGROUND: We previously reported that CEA kinetics are a marker of progressive disease (PD) in metastatic colorectal cancer (mCRC). This study was specifically designed to confirm CEA kinetics for predicting PD and to evaluate CA19-9, cell-free DNA
Autor:
Yuyao Yuan, Juntuo Zhou, Guangxi Wang, Jianyuan Luo, Yongmei Song, Huajie Song, Zitong Zhao, Liyan Xue, Yuxin Yin, Pang Ruifang
Publikováno v:
Br J Cancer
Background Oesophageal cancer (EC) ranks high in both morbidity and mortality. A non-invasive and high-sensitivity diagnostic approach is necessary to improve the prognosis of EC patients. Methods A total of 525 serum samples were subjected to lipido
Autor:
Vincent Cheung, Rosalin Cooper, Isar Nassiri, Anna Olsson-Brown, Robert A. Watson, Mark Coles, Umair Akbani, Mark R. Middleton, Chelsea A Taylor, Joseph J. Sacco, Weiyu Ye, Oliver Brain, Rubeta N Matin, Robert D Morgan, Miranda Payne, Benjamin P. Fairfax, Nicholas Coupe
Publikováno v:
British Journal of Cancer
BRITISH JOURNAL OF CANCER
BRITISH JOURNAL OF CANCER
Background Immune checkpoint blockers (ICBs) activate CD8+ T cells, eliciting both anti-cancer activity and immune-related adverse events (irAEs). The relationship of irAEs with baseline parameters and clinical outcome is unclear. Methods Retrospecti
Pharmaceutical immunoglobulin G impairs anti-carcinoma activity of oxaliplatin in colon cancer cells
Autor:
Yuru Shang, Christina S Mullins, Peng Gong, Brigitte Vollmar, Xianbin Zhang, Lili Lu, Dietmar Zechner, Ke Jiang, Mathias Krohn, Michael Linnebacher, Stephanie Matschos
Publikováno v:
British Journal of Cancer
Background Recent evidence proves that intravenous human immunoglobulin G (IgG) can impair cancer cell viability. However, no study evaluated whether IgG application benefits cancer patients receiving chemotherapeutics. Methods Influence of pharmaceu
Autor:
Muntasir Mamun Majumder, Romika Kumari, Nina N. Nupponen, Raija Silvennoinen, Pekka Anttila, Juha Lievonen, Fredrik Lehmann, Caroline A. Heckman
Publikováno v:
British Journal of Cancer
Background Esterase enzymes differ in substrate specificity and biological function and may display dysregulated expression in cancer. This study evaluated the biological significance of esterase expression in multiple myeloma (MM). Methods For gene
Autor:
Yingying Gao, Yanni Hao, Mengjuan Yuan, Ting Li, Lingfang Niu, Luo Li, Chunli Luo, Chaowen Yu, Xiaohou Wu, Nanjing Liu, Zhen Quan
Publikováno v:
British Journal of Cancer
Background The role of HOX transcript antisense RNA (HOTAIR) has been proven to be important in tumorigenesis. However, how this molecule promotes metastasis and invasion in PCa is still unclear. Methods The relationship between HOTAIR and hepatocell
Autor:
Anna Larissa N. Niemeijer, Sara Sahba, Adrianus J. de Langen, Egbert F. Smit, Birgit I. Lissenberg-Witte, Erik Thunnissen
Publikováno v:
British Journal of Cancer, 123(3), 392-402. SPRINGERNATURE
Niemeijer, A L N, Sahba, S, Smit, E F, Lissenberg-Witte, B I, de Langen, A J & Thunnissen, E 2020, ' Association of tumour and stroma PD-1, PD-L1, CD3, CD4 and CD8 expression with DCB and OS to nivolumab treatment in NSCLC patients pre-treated with chemotherapy ', British Journal of Cancer, vol. 123, no. 3, pp. 392-402 . https://doi.org/10.1038/s41416-020-0888-5
British Journal of Cancer, 123(3), 392-402. Nature Publishing Group
British Journal of Cancer
Niemeijer, A L N, Sahba, S, Smit, E F, Lissenberg-Witte, B I, de Langen, A J & Thunnissen, E 2020, ' Association of tumour and stroma PD-1, PD-L1, CD3, CD4 and CD8 expression with DCB and OS to nivolumab treatment in NSCLC patients pre-treated with chemotherapy ', British Journal of Cancer, vol. 123, no. 3, pp. 392-402 . https://doi.org/10.1038/s41416-020-0888-5
British Journal of Cancer, 123(3), 392-402. Nature Publishing Group
British Journal of Cancer
Background Immune checkpoint inhibitors are most beneficial in patients with high tumour PD-L1 expression. However, the use of PD-L1 expression is not straightforward. We investigated PD-L1 expression and immune cell (IC) infiltrates in non-small-cel
Autor:
Bei-Bei Lv, Ran-Ran Ma, Duan-Bo Shi, Hui Zhang, Peng Gao, Guo-Hao Zhang, Xiang-Yu Guo, Hai-Ting Liu
Publikováno v:
British Journal of Cancer
Background Accumulating evidence demonstrated that long noncoding RNAs (lncRNAs) played important regulatory roles in many cancer types. However, the role of lncRNAs in gastric cancer (GC) progression remains unclear. Methods RT-qPCR assay was perfor