Zobrazeno 1 - 10
of 660
pro vyhledávání: ''
Autor:
Laura E. Fischer, Sebastian Stintzing, Ludwig Fischer von Weikersthal, Dominik P. Modest, Thomas Decker, Alexander Kiani, Florian Kaiser, Salah-Eddin Al-Batran, Tobias Heintges, Christian Lerchenmüller, Christoph Kahl, Gernot Seipelt, Frank Kullmann, Martina Stauch, Werner Scheithauer, Clemens Giessen-Jung, Jens Uhlig, Bettina Peuser, Claudio Denzlinger, Arndt Stahler, Lena Weiss, Kathrin Heinrich, Swantje Held, Andreas Jung, Thomas Kirchner, Volker Heinemann
Publikováno v:
British Journal of Cancer. 127:836-843
Summary Background The evidence on the efficacy of anticancer therapy is limited in older patients with metastatic colorectal cancer (mCRC). This retrospective analysis of phase III FIRE-3 trial assesses the efficacy of FOLFIRI plus either cetuximab
Publikováno v:
Br J Cancer
BACKGROUND: Acknowledging the role of inflammation in colorectal carcinogenesis, this study aimed to evaluate the associations between diet-associated inflammation, as measured by the energy-adjusted dietary inflammatory index (E-DII(TM)), and distin
Autor:
Xiaomeng Zhang, Xue Li, Yazhou He, Philip J. Law, Susan M. Farrington, Harry Campbell, Ian P. M. Tomlinson, Richard S. Houlston, Malcolm G. Dunlop, Maria Timofeeva, Evropi Theodoratou
Publikováno v:
Zhang, X, Li, X, He, Y, Law, P, Farrington, S M, Campbell, H, Tomlinson, I P M, Houlston, R S, Dunlop, M G, Timofeeva, M & Theodoratou, E 2021, ' Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank ', British Journal of Cancer . https://doi.org/10.1038/s41416-021-01655-9
Background Associations between colorectal cancer (CRC) and other health outcomes have been reported, but these may be subject to biases, or due to limitations of observational studies. Methods We set out to determine whether genetic predisposition t
Autor:
Helga E. Laszlo, Edward Seward, Ruth M. Ayling, Jennifer Lake, Aman Malhi, Clare Stephens, Kathy Pritchard-Jones, Donna Chung, Allan Hackshaw, Michael Machesney
Publikováno v:
British Journal of Cancer. 126:736-743
Background We evaluated whether faecal immunochemical testing (FIT) can rule out colorectal cancer (CRC) among patients presenting with ‘high-risk’ symptoms requiring definitive investigation. Methods Three thousand five hundred and ninety-six sy
Autor:
Saisai Wang, Dong Chen, Zhou Tong, Yongfeng Ding, Lulu Liu, Ruyi Zhang, Min Zhang, Xuanwen Bao, Weijia Fang, Peng Zhao, Hangyu Zhang, Xiaolin Li, Xiaohu Zhou, Yi Zheng, Benfeng Li, Jian Ruan, Xiaofei Cheng
Publikováno v:
Br J Cancer
BACKGROUND: Colorectal neuroendocrine carcinomas (CRNECs) are highly aggressive tumours with poor prognosis and low incidence. To date, the genomic landscape and molecular pathway alterations have not been elucidated. METHODS: Tissue sections and cli
Autor:
David Groshar, Jennifer Y. Wo, Motaz Qadan, Krista E Suarez-Weiss, James C. Cusack, Heike E. Daldrup-Link, Ricciardi Rocco, Amirkasra Mojtahed, Robin Striar, Liliana Bordeianou, Lale Umutlu, Felipe S. Furtado, Mark Anderson, Mark Vangel, Onofrio A. Catalano, Cristina R. Ferrone, Lawrence S. Blaszkowsky, Theodore S. Hong, Jeffrey W. Clark
Publikováno v:
Br J Cancer
Background Oligometastatic colorectal cancer (CRC) is potentially curable and demands individualised strategies. Methods This single-centre retrospective study investigated if positron emission tomography (PET)/magnetic resonance imaging (MR) had a c
Autor:
Emilie S Zoltick, Kimmie Ng, Stephanie A. Smith-Warner, Jeffrey A. Meyerhardt, Andrew T. Chan, Meir J. Stampfer, Chen Yuan, Molin Wang, Shuji Ogino, Charles S. Fuchs, Kana Wu, Edward Giovannucci
Publikováno v:
Br J Cancer
BACKGROUND: The influence of a high sugar diet on colorectal cancer (CRC) survival is unclear. METHODS: Among 1463 stage I–III CRC patients from the Nurses’ Health Study and Health Professionals Follow-up Study, we estimated hazard ratios (HRs) a
Autor:
Alberto Zaniboni, Chiara Cremolini, Gianluca Tomasello, Samanta Cupini, Laura Fanchini, Beatrice Borelli, Sara Lonardi, Gianluca Masi, Daniele Rossini, Angela Buonadonna, Carlotta Antoniotti, Veronica Conca, Gemma Zucchelli, Alfredo Falcone, Federica Marmorino, Margherita Ambrosini, Salvatore Caponnetto, Daniele Santini, Cosimo Rasola, Roberto Moretto
Publikováno v:
Br J Cancer
BACKGROUND: In mCRC, CEA is used to monitor response to systemic therapy together with imaging. After the end of induction, no major improvement in tumour shrinkage is expected, and the availability of a marker able to predict progressive disease (PD
Autor:
Xinchen Wang, Qing Liu, Katja Fall, Helga Zoega, Omid Sadr-Azodi, Oskar Halfdanarson, Lars Engstrand, Nele Brusselaers
Publikováno v:
Br J Cancer
The British journal of cancer
The British journal of cancer
Background Proton pump inhibitors (PPIs) are associated with microbiome changes of the gut, which in turn may affect the progression of colorectal cancer (CRC). This study aims to assess the associations between PPI use and all-cause and CRC-specific
Autor:
David Sefrioui, Ludivine Beaussire, André Gillibert, France Blanchard, Emmanuel Toure, Céline Bazille, Anne Perdrix, Frédéric Ziegler, Alice Gangloff, Mélanie Hassine, Caroline Elie, Anne-Laure Bignon, Aurélie Parzy, Philippe Gomez, Caroline Thill, Florian Clatot, Jean-Christophe Sabourin, Thierry Frebourg, Jacques Benichou, Karine Bouhier-Leporrier, Marie-Pierre Gallais, Nasrin Sarafan-Vasseur, Pierre Michel, Frédéric Di Fiore
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2021, ⟨10.1038/s41416-021-01431-9⟩
Br J Cancer
British Journal of Cancer, Cancer Research UK, 2021, ⟨10.1038/s41416-021-01431-9⟩
Br J Cancer
BACKGROUND: We previously reported that CEA kinetics are a marker of progressive disease (PD) in metastatic colorectal cancer (mCRC). This study was specifically designed to confirm CEA kinetics for predicting PD and to evaluate CA19-9, cell-free DNA