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Autor:
Masaoki Ito, Andrés F. Cardona, Andrés Aguilar, Jordi Codony-Servat, Mariacarmela Santarpia, Rafael Rosell, Carlos González Pedraz, Oscar Arrieta
Publikováno v:
British Journal of Cancer
Epidermal growth factor receptor (EGFR) mutations in lung adenocarcinoma are a frequent class of driver mutations. Single EGFR tyrosine kinase inhibitor (TKI) provides substantial clinical benefit, but almost nil radiographic complete responses. Pati
Publikováno v:
British Journal of Cancer
Background Cancer stem cells (CSCs) are related to the patient’s prognosis, recurrence and therapy resistance in oesophageal squamous cell carcinoma (ESCC). Although increasing evidence suggests that aspirin (acetylsalicylic acid, ASA) could lower
Publikováno v:
British Journal of Cancer
The gut microbiome (GM) has been implicated in a vast number of human pathologies and has become a focus of oncology research over the past 5 years. The normal gut microbiota imparts specific function in host nutrient metabolism, xenobiotic and drug
Publikováno v:
British Journal of Cancer
Immune checkpoint inhibitors (ICIs) have altered the treatment paradigm across a range of tumour types, including gastro-oesophageal cancers. For patients with any cancer type who respond, ICIs can confer long-term disease control and significantly i
Autor:
Andreas Schneeweiss, Wolfgang Wick, Georg Martin Haag, Joachim Wiskemann, Jana Müller, Karen Steindorf, Markus Weiler
Publikováno v:
British Journal of Cancer
Background Chemotherapy-induced peripheral neuropathy (CIPN) is a common, unpleasant and usually long-lasting side effect of neurotoxic chemotherapeutic agents. This study aimed to investigate the preventive potential of sensorimotor- (SMT) and resis
Autor:
Lili Gao, Yi Sui, Wei Hu, Tao Yang, Dejian Li, Rujian Zhu, Hongbo Zhu, Qingtong Yi, Qinghua You, Wei Zhang, Tao Tang, Shengjuan Zhu
Publikováno v:
British Journal of Cancer
Background Metastasis is the major cause of treatment failure and cancer-related deaths in prostate cancer (PCa) patients. Our previous study demonstrated that a CD44+ subpopulation isolated from PCa cells or tumours possesses both stem cell properti
Publikováno v:
British Journal of Cancer
Although low risk localised prostate cancer has an excellent prognosis owing to effective treatments, such as surgery, radiation, cryosurgery and hormone therapy, metastatic prostate cancer remains incurable. Existing therapeutic regimens prolong lif
Publikováno v:
British Journal of Cancer
Colorectal cancer represents the second leading cause of cancer-related death worldwide. The therapeutic field of immuno-oncology has rapidly gained momentum, with strikingly promising results observed in clinical practice. Increasing emphasis has be
Autor:
Stefan J. Marciniak, David Fairen-Jimenez, Xiewen Liu, Robert C. Rintoul, Marie Shamseddin, Marko Nikolic, Arsalan A. Azad, Joanna Obacz, Emily Linnane, Doris Rassl, Henry Yung
Publikováno v:
British Journal of Cancer
Funder: British Lung Foundation (BLF); doi: https://doi.org/10.13039/501100000351
Funder: Royal Society through a University Research Fellowship and the Engineering and Physical Sciences Research Council (EPRSC)
Funder: China Scholarship Co
Funder: Royal Society through a University Research Fellowship and the Engineering and Physical Sciences Research Council (EPRSC)
Funder: China Scholarship Co
Autor:
Yee Chao, Kun Han Lee, Chun Chi Lin, Hao Wei Teng, Hung Hsin Lin, Jeng Kai Jiang, Shih Ching Chang, Wei Shone Chen, Sheng Chieh Huang, Shung Haur Yang, Huann Sheng Wang, Hou Hsuan Cheng, Yuan Tzu Lan
Publikováno v:
British Journal of Cancer. 125:816-825
Background Clinically, metastatic rectal cancer has been considered a subset of left-sided colon cancer. However, heterogeneity has been proposed to exist between high and middle/low rectal cancers. We aimed to examine the efficacy of anti-epidermal