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Autor:
J Meyer, Elaine F. Harkness, Yit Yoong Lim, Susan M. Astley, Mary E. Wilson, Julie Morris, M Bydder, CE Mercer, Anthony J. Maxwell
Publikováno v:
Breast Cancer Research : BCR
Previous work has demonstrated that approximately 14% of women who attend their first breast screening appointment fail to attend the next appointment. It is well recognised that some women experience marked discomfort or pain during mammography whic
Publikováno v:
Breast Cancer Research : BCR
Introduction Over the last decade several breast cancer risk alleles have been identified which has led to an increased interest in individualised risk prediction for clinical purposes. Methods We investigate the performance of an up-to-date 18 breas
Autor:
Mårten Fernö, Pär-Ola Bendahl, Åke Borg, Lao H. Saal, Cecilia Hegardt, Dorthe Grabau, Gabriella Honeth, Kristina Lövgren, Markus Ringnér, Sofia K. Gruvberger-Saal
Publikováno v:
Breast Cancer Research. 10(3)
Human breast tumors are heterogeneous and consist of phenotypically diverse cells. Breast cancer cells with a CD44+/CD24- phenotype have been suggested to have tumor-initiating properties with stem cell-like and invasive features, although it is uncl
Autor:
Moustapha Kassem, Marie Christine Klitgaard, René Villadsen, Mikkel Morsing, Ole W. Petersen, Abbas Jafari, Lone Rønnov-Jessen
Publikováno v:
Morsing, M, Klitgaard, M C, Jafari Kermani, A, Villadsen, R, Kassem, M S E-D, Petersen, O W & Rønnov-Jessen, L 2016, ' Evidence of two distinct functionally specialized fibroblast lineages in breast stroma ', Breast Cancer Research (Online), vol. 18, 108 . https://doi.org/10.1186/s13058-016-0769-2
Breast Cancer Research : BCR
Morsing, M, Klitgaard, M C, Jafari, A, Villadsen, R, Kassem, M, Petersen, O W & Rønnov-Jessen, L 2016, ' Evidence of two distinct functionally specialized fibroblast lineages in breast stroma ', Breast Cancer Research (Online), vol. 18, 108 . https://doi.org/10.1186/s13058-016-0769-2
Breast Cancer Research : BCR
Morsing, M, Klitgaard, M C, Jafari, A, Villadsen, R, Kassem, M, Petersen, O W & Rønnov-Jessen, L 2016, ' Evidence of two distinct functionally specialized fibroblast lineages in breast stroma ', Breast Cancer Research (Online), vol. 18, 108 . https://doi.org/10.1186/s13058-016-0769-2
Background The terminal duct lobular unit (TDLU) is the most dynamic structure in the human breast and the putative site of origin of human breast cancer. Although stromal cells contribute to a specialized microenvironment in many organs, this compon
Autor:
Anthony J. Swerdlow, Alan Ashworth, James Griffin, Emily McFadden, Minouk J. Schoemaker, Michael Jones, Lauren B. Wright
Publikováno v:
Breast Cancer Research : BCR
Background Women diagnosed with breast cancer frequently attribute their cancer to psychological stress, but scientific evidence is inconclusive. We investigated whether experienced frequency of stress and adverse life events affect subsequent breast
Autor:
Karina Cox, Mohamed Hashem, Neal Chayya, P. Mills, Sarah Kirwan, Tania De'Silva, Nick Wakeham
Publikováno v:
Breast Cancer Research : BCR
At Maidstone and Tunbridge Wells NHS Trust, all newly diagnosed breast cancer patients with a normal grey-scale axillary ultrasound have a procedure to identify and biopsy sentinel lymph nodes (SLN) using contrast-enhanced ultrasound (CEUS).
Publikováno v:
Breast Cancer Research : BCR
There is a reported increased incidence of contralateral disease at presentation of invasive lobular cancer (ILC). In our unit breast MRI is undertaken to assess the extent of all newly diagnosed ILC. If mastectomy is planned MRI is still carried out
Publikováno v:
Breast cancer research : BCR
Background Stromal fibroblasts can contribute to tumor invasion through the release of matrix metalloproteinases (MMPs). Population studies have suggested that single nucleotide polymorphisms (SNPs) in MMP genes influence levels of expression and may
Autor:
Stuart J. Schnitt, Anne C Deitz, James L. Connolly, Graham A. Colditz, Laura C. Collins, Yineng Fu, Mark Galan, Heather J. Baer, Jonathan Marotti, Laurie Galaburda, Rulla M. Tamimi
Publikováno v:
Breast Cancer Research : BCR
Introduction At least four major categories of invasive breast cancer that are associated with different clinical outcomes have been identified by gene expression profiling: luminal A, luminal B, human epidermal growth factor receptor 2 (HER2) and ba
Autor:
Evagelos Tzoracoleftherakis, Athanassios Polychronis, Helen Gogas, Spyros Lazarou, Grigorios Xepapadakis, Christos Markopoulos, Angeliki Sarantopoulou, Kyriakos Kalogerakos, V. Zobolas, Basileios Venizelos, Nikolaos Siasos, John Misitzis, Zoh Antonopoulou, Dimitrios Koukouras, J. Papadiamantis, Urania Dafni
Publikováno v:
Breast Cancer Research : BCR
Introduction The aim of this multicenter, phase III, prospective open label clinical trial was to investigate the effect of risedronate (R) on bone mineral density (BMD) in postmenopausal, early breast cancer (BC) patients scheduled to receive anastr