Zobrazeno 101 - 110
of 337
pro vyhledávání: ''
Autor:
Esther M. John, Melissa C. Southey, Elena Samiltchuk, Celia M. T. Greenwood, Valentina Kriukov, Ayesha Salleh, Rashmi V. Parekh, Linda Linton, Lisa J. Martin, Norman F. Boyd, Apostolos Dimitromanolakis, Carmel Apicella, Johanna M. Rommens, John L. Hopper, Irene L. Andrulis, Andrew D. Paterson
Publikováno v:
Breast Cancer Research : BCR
Introduction Mammographic breast density is a highly heritable (h2 > 0.6) and strong risk factor for breast cancer. We conducted a genome-wide linkage study to identify loci influencing mammographic breast density (MD). Methods Epidemiological data w
Autor:
Suhad Ali, Ani Arakelian, Amal A Al-Odaini, Meiou Dai, Jean-Jacques Lebrun, Shafaat A. Rabbani
Publikováno v:
Breast Cancer Research : BCR
Introduction Tumor cell migration and invasion are critical initiation steps in the process of breast cancer metastasis, the primary cause of breast cancer morbidity and death. Here we investigated the role of p21Cip1 (p21), a member of the core cell
Autor:
Fredrik Granath, Andor Pivarcsi, Clara Ibel Chamorro, Annelie Liljegren, Günther Weber, Romuald Mentaverri, Samuel Rotstein, Bengt Sandstedt, Zuzana Saidak, Fabio Sánchez, Mona Ståhle, Sami Zreika
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research
Breast Cancer Research, BioMed Central, 2009, pp.R6
Breast Cancer Research
Breast Cancer Research, BioMed Central, 2009, pp.R6
Introduction Human cathelicidin antimicrobial protein, hCAP18, and its C-terminal peptide LL-37 is a multifunctional protein. In addition to being important in antimicrobial defense, it induces chemotaxis, stimulates angiogenesis and promotes tissue
Autor:
Tayebeh Pourmotabbed, Miranda A. Hallett, Tiffany N. Seagroves, Hisashi Hasegawa, Luciana P. Schwab, Bin Teng
Publikováno v:
Breast Cancer Research : BCR
Introduction Despite continued improvements in diagnosis, surgical techniques, and chemotherapy, breast cancer patients are still overcome by cancer metastasis. Tumor cell proliferation, invasion and metastasis are mediated, at least in part, through
Autor:
Jennifer M. Giltnane, Harriet M. Kluger, Yasmine Nadler, Christopher B. Moeder, David L. Rimm, Robert L. Camp, Yuval Kluger
Publikováno v:
Breast Cancer Research : BCR
Introduction Bcl-2 antanogene-1 (Bag-1) binds the anti-apoptotic mediator Bcl-2, and enhances its activity. Bcl-2 and Bag-1 are associated with chemotherapy resistance in cancer cells. Drugs that target Bcl-2 are currently in clinical development. Th
Publikováno v:
Breast Cancer Research : BCR
The aim was to investigate the impact of index of multiple deprivation (IMD) and ethnicity on breast cancer screening uptake in the North West of England.
Autor:
Ian Spendlove, Zahra Madjd, Nicholas F S Watson, Lindy G. Durrant, Ian O. Ellis, Tina Parsons
Publikováno v:
Breast Cancer Research
Introduction There is sufficient evidence that blood group related Lewis antigens are tumour-associated molecules. The Lewisy and Lewisb antigens are complex carbohydrates that are over-expressed by breast, lung, colon and ovarian cancers. The SC101
Autor:
Naoyuki Danbara, Hideto Senzaki, Hideho Takada, Takashi Yuri, Norihisa Uehara, Miki Tsujita-Kyutoku, Teruo Miyazawa, Takahiko Hada, Yutaka Ogawa, Yasuhiko Kiyozuka, Airo Tsubura
Publikováno v:
Breast Cancer Research
Introduction The present study was conducted to examine the effect of conjugated docosahexaenoic acid (CDHA) on cell growth, cell cycle progression, mode of cell death, and expression of cell cycle regulatory and/or apoptosis-related proteins in KPL-
Autor:
Zoann Nugent, Tarek Bader, Anuraag Shrivastav, Peter H. Watson, Mary Christine Bruce, Leigh C. Murphy, Srinivas V Seekallu, Danira Jaksic, Carla Penner
Publikováno v:
Breast Cancer Research : BCR
Introduction A phosphorylation score for estrogen receptor-alpha (ERα), called P7 score, was shown previously to be an independent prognostic factor in breast cancer patients treated with tamoxifen. Since mechanistic target of rapamycin (mTOR) activ
Autor:
David I. Rodenhiser, Ann F. Chambers, Bekim Sadikovic, Ariel Mendlowitz, Wendy Kennette, Alan B. Tuck, Joseph Andrews
Publikováno v:
Biochemistry Publications
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Introduction Breast cancer metastasis is a complex, multi-step biological process. Genetic mutations along with epigenetic alterations in the form of DNA methylation patterns and histone modifications contribute to metastasis-related gene expression