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Publikováno v:
Breast Cancer Research
Background Viruses including Epstein–Barr virus (EBV), a human equivalent of murine mammary tumour virus (MMTV) and human papillomavirus (HPV) have been implicated in the aetiology of human breast cancer. We report the presence of HPV DNA sequences
Publikováno v:
Breast Cancer Research
Menopausal hormone therapy (HT) is typically withheld from breast cancer survivors because of concerns about risk for recurrence. Our objectives were to estimate the effects of HT on recurrence in breast cancer survivors and to examine the reliabilit
Autor:
Mario Giuliano, Emilia Montagna, Diego D'Agostino, Sabino De Placido, Giuseppe Cancello, Monica Plaitano, Giuseppe Di Lorenzo, Michele De Laurentiis, Antonio Giordano
Publikováno v:
Breast Cancer Research : BCR
INTRODUCTION: We performed a retrospective analysis of HER2-overexpressing metastatic breast cancer patients to describe clinical outcomes of those who, despite progression of the disease (PD), maintained trastuzumab for multiple chemotherapy lines.
Publikováno v:
Breast Cancer Research
Introduction Mammographic density is a strong, independent risk factor for breast cancer. A critical unanswered question is whether cancers tend to arise in mammographically dense tissue (i.e. are densities directly related to risk or are they simply
Publikováno v:
Breast Cancer Research : BCR
Introduction Characterizing and differentiating between malignant tumors, benign tumors, and normal breast tissue is increasingly important in the patient presenting with breast problems. Near-infrared diffuse optical imaging and spectroscopy is capa
Publikováno v:
Breast Cancer Research : BCR
Introduction Proteasome inhibition provides an attractive approach to cancer therapy and may have application in the treatment of breast cancer. However, results of recent clinical trials to evaluate the effect of the proteasome inhibitor Bortezomib
Autor:
M. Villalobos, José Antonio Muñoz-Gámez, R. Guerrero, M. T. Valenzuela, José Mariano Ruiz de Almodóvar, Escarlata López, María Isabel Núñez, Joaquina Martínez-Galán, Rosario Del Moral, Francisco Javier Oliver, David Martín-Oliva
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Breast Cancer Research
instname
Breast Cancer Research
This article is online at: http://breast-cancer-research.com/content/7/5/R690
[Introduction] Radiotherapy outcomes might be further improved by a greater understanding of the individual variations in normal tissue reactions that determine tolera
[Introduction] Radiotherapy outcomes might be further improved by a greater understanding of the individual variations in normal tissue reactions that determine tolera
Autor:
Laurence N. Kolonel, Song-Yi Park, Melissa A. Little, Shannon M. Conroy, Gertraud Maskarinec, Ian Pagano
Publikováno v:
Breast Cancer Research : BCR
Introduction Mammographic density, a strong predictor for breast cancer incidence, may also worsen prognosis in women with breast cancer. This prospective analysis explored the effect of prediagnostic mammographic density among 607 breast cancer case
Autor:
Sophia Agelaki, Antonia Kalykaki, A. Xyrafas, Emmanouil Saloustros, Kostas Kalbakis, Galatea Kallergi, Dimitris Mavroudis, Stella Apostolaki, M. Perraki, Vassilis Georgoulias
Publikováno v:
Breast Cancer Research : BCR
Background The detection of cytokeratin-19 (CK-19) mRNA-positive circulating tumor cells (CTC) before and/or after adjuvant chemotherapy in patients with operable breast cancer is associated with poor clinical outcome. Reliable prognostic markers for
Autor:
Mårten Fernö, Pär-Ola Bendahl, Åke Borg, Lao H. Saal, Cecilia Hegardt, Dorthe Grabau, Gabriella Honeth, Kristina Lövgren, Markus Ringnér, Sofia K. Gruvberger-Saal
Publikováno v:
Breast Cancer Research. 10(3)
Human breast tumors are heterogeneous and consist of phenotypically diverse cells. Breast cancer cells with a CD44+/CD24- phenotype have been suggested to have tumor-initiating properties with stem cell-like and invasive features, although it is uncl