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Publikováno v:
Breast Cancer Research
Background Viruses including Epstein–Barr virus (EBV), a human equivalent of murine mammary tumour virus (MMTV) and human papillomavirus (HPV) have been implicated in the aetiology of human breast cancer. We report the presence of HPV DNA sequences
Publikováno v:
Breast Cancer Research
Introduction Mammographic density is a strong, independent risk factor for breast cancer. A critical unanswered question is whether cancers tend to arise in mammographically dense tissue (i.e. are densities directly related to risk or are they simply
Publikováno v:
Breast Cancer Research : BCR
Introduction Characterizing and differentiating between malignant tumors, benign tumors, and normal breast tissue is increasingly important in the patient presenting with breast problems. Near-infrared diffuse optical imaging and spectroscopy is capa
Autor:
Stephanie A. Kennedy, Jennifer Gallagher, Lee G. Wilke, Marlee K. Junker, Nimmi Ramanujam, Torre Michelle Bydlon, Joseph Geradts, J. Quincy Brown, William T. Barry
Publikováno v:
Breast Cancer Research : BCR
Introduction Residual cancer following breast conserving surgery increases the risk of local recurrence and mortality. Margin assessment presents an unmet clinical need. Breast tissue is markedly heterogeneous, which makes distinguishing small foci o
Autor:
Moustapha Kassem, Marie Christine Klitgaard, René Villadsen, Mikkel Morsing, Ole W. Petersen, Abbas Jafari, Lone Rønnov-Jessen
Publikováno v:
Morsing, M, Klitgaard, M C, Jafari Kermani, A, Villadsen, R, Kassem, M S E-D, Petersen, O W & Rønnov-Jessen, L 2016, ' Evidence of two distinct functionally specialized fibroblast lineages in breast stroma ', Breast Cancer Research (Online), vol. 18, 108 . https://doi.org/10.1186/s13058-016-0769-2
Breast Cancer Research : BCR
Morsing, M, Klitgaard, M C, Jafari, A, Villadsen, R, Kassem, M, Petersen, O W & Rønnov-Jessen, L 2016, ' Evidence of two distinct functionally specialized fibroblast lineages in breast stroma ', Breast Cancer Research (Online), vol. 18, 108 . https://doi.org/10.1186/s13058-016-0769-2
Breast Cancer Research : BCR
Morsing, M, Klitgaard, M C, Jafari, A, Villadsen, R, Kassem, M, Petersen, O W & Rønnov-Jessen, L 2016, ' Evidence of two distinct functionally specialized fibroblast lineages in breast stroma ', Breast Cancer Research (Online), vol. 18, 108 . https://doi.org/10.1186/s13058-016-0769-2
Background The terminal duct lobular unit (TDLU) is the most dynamic structure in the human breast and the putative site of origin of human breast cancer. Although stromal cells contribute to a specialized microenvironment in many organs, this compon
Autor:
Stuart J. Schnitt, Anne C Deitz, James L. Connolly, Graham A. Colditz, Laura C. Collins, Yineng Fu, Mark Galan, Heather J. Baer, Jonathan Marotti, Laurie Galaburda, Rulla M. Tamimi
Publikováno v:
Breast Cancer Research : BCR
Introduction At least four major categories of invasive breast cancer that are associated with different clinical outcomes have been identified by gene expression profiling: luminal A, luminal B, human epidermal growth factor receptor 2 (HER2) and ba
Publikováno v:
Breast Cancer Research : BCR
The aim of this study is to compare the performance of Sectra and Hologic digital mammography, two different technologies introduced to Breast Test Wales in 2012 for breast cancer screening. Specifically, any variation in findings and whether differe
Publikováno v:
Breast Cancer Research : BCR
Introduction Transducin (β)-like 1 X-linked receptor 1(TBLR1) is an F-box-like and WD repeat-containing protein which functions as a switch in transcriptional activation, However, the clinical significance and biological role of TBLR1 in breast canc
Autor:
Kanji Nakatsu, Abdi Ghaffari, Maaike Hum, Navid Liaghati, Yolanda Madarnas, Victoria Hoskin, Alvin Szeto, Sandip SenGupta, Bruce E. Elliott, David P. LeBrun
Publikováno v:
Breast Cancer Research : BCR
Recent evidence suggests that tumour lymphangiogenesis promotes lymph node metastasis, a major prognostic factor for survival of breast cancer patients. However, signaling mechanisms involved in tumour-induced lymphangiogenesis remain poorly understo
Autor:
Greg Finak, Sarkis Meterissian, Morag Park, Michael Hallett, Karim Khetani, Margarita Souleimanova, Svetlana Sadekova, Atilla Omeroglu, Francois Pepin, Brent P. Zabolotny, Fawaz Halwani
Publikováno v:
Breast Cancer Research
Introduction The role of the cellular microenvironment in breast tumorigenesis has become an important research area. However, little is known about gene expression in histologically normal tissue adjacent to breast tumor, if this is influenced by th