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Publikováno v:
Breast Cancer Research
Menopausal hormone therapy (HT) is typically withheld from breast cancer survivors because of concerns about risk for recurrence. Our objectives were to estimate the effects of HT on recurrence in breast cancer survivors and to examine the reliabilit
Autor:
Mario Giuliano, Emilia Montagna, Diego D'Agostino, Sabino De Placido, Giuseppe Cancello, Monica Plaitano, Giuseppe Di Lorenzo, Michele De Laurentiis, Antonio Giordano
Publikováno v:
Breast Cancer Research : BCR
INTRODUCTION: We performed a retrospective analysis of HER2-overexpressing metastatic breast cancer patients to describe clinical outcomes of those who, despite progression of the disease (PD), maintained trastuzumab for multiple chemotherapy lines.
Publikováno v:
Breast Cancer Research
Introduction Mammographic density is a strong, independent risk factor for breast cancer. A critical unanswered question is whether cancers tend to arise in mammographically dense tissue (i.e. are densities directly related to risk or are they simply
Autor:
Jinbo Chen, Michael Kalos, Joshua Bauml, Angela DeMichele, Susan Q. Li, Jun J. Mao, Jean D. Boyer, Lu Chen
Publikováno v:
Breast Cancer Research : BCR
Introduction Arthralgia is a common toxicity among women taking aromatase inhibitors (AIs) and can lead to premature discontinuation of therapy. We evaluated the association between arthralgia, co-morbid fatigue and/or insomnia, and inflammatory biom
Autor:
Rochelle E. Curtis, Mark M. Huycke, Bassam Ghabach, William F. Anderson, Jackie A. Lavigne, Graça M. Dores
Publikováno v:
Breast Cancer Research : BCR
Introduction Adenoid cystic carcinoma of the breast (breast-ACC) is a rare and special type of basal-like tumor for which scant population-based descriptive data exist. We sought to provide new population-based information on breast-ACC incidence, re
Autor:
Janet R. Daling, Danielle M. Friedrichsen, Elaine A. Ostrander, Kathleen E. Malone, David R. Doody
Publikováno v:
Breast Cancer Research
Introduction The cell-cycle checkpoint kinase (CHEK)2 protein truncating mutation 1100delC has been associated with increased risk for breast or prostate cancer. Multiple studies have found an elevated frequency of the 1100delC variant in specific st
Publikováno v:
Breast Cancer Research : BCR
Introduction Proteasome inhibition provides an attractive approach to cancer therapy and may have application in the treatment of breast cancer. However, results of recent clinical trials to evaluate the effect of the proteasome inhibitor Bortezomib
Autor:
M. Villalobos, José Antonio Muñoz-Gámez, R. Guerrero, M. T. Valenzuela, José Mariano Ruiz de Almodóvar, Escarlata López, María Isabel Núñez, Joaquina Martínez-Galán, Rosario Del Moral, Francisco Javier Oliver, David Martín-Oliva
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Breast Cancer Research
instname
Breast Cancer Research
This article is online at: http://breast-cancer-research.com/content/7/5/R690
[Introduction] Radiotherapy outcomes might be further improved by a greater understanding of the individual variations in normal tissue reactions that determine tolera
[Introduction] Radiotherapy outcomes might be further improved by a greater understanding of the individual variations in normal tissue reactions that determine tolera
Autor:
Laurence N. Kolonel, Song-Yi Park, Melissa A. Little, Shannon M. Conroy, Gertraud Maskarinec, Ian Pagano
Publikováno v:
Breast Cancer Research : BCR
Introduction Mammographic density, a strong predictor for breast cancer incidence, may also worsen prognosis in women with breast cancer. This prospective analysis explored the effect of prediagnostic mammographic density among 607 breast cancer case
Autor:
David Van Den Berg, Malcolm C. Pike, Yuri R. Parisky, Wendy J. Mack, Christopher A. Haiman, Sue A. Ingles, Sarah J. Lord, Wei Wang, Giske Ursin, Howard N. Hodis
Publikováno v:
Breast Cancer Research
Introduction Mammographic density is a strong independent risk factor for breast cancer, and can be modified by hormonal exposures. Identifying genetic variants that determine increases in mammographic density in hormone users may be important in und