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Publikováno v:
Breast Cancer Research
Menopausal hormone therapy (HT) is typically withheld from breast cancer survivors because of concerns about risk for recurrence. Our objectives were to estimate the effects of HT on recurrence in breast cancer survivors and to examine the reliabilit
Autor:
Jinbo Chen, Michael Kalos, Joshua Bauml, Angela DeMichele, Susan Q. Li, Jun J. Mao, Jean D. Boyer, Lu Chen
Publikováno v:
Breast Cancer Research : BCR
Introduction Arthralgia is a common toxicity among women taking aromatase inhibitors (AIs) and can lead to premature discontinuation of therapy. We evaluated the association between arthralgia, co-morbid fatigue and/or insomnia, and inflammatory biom
Autor:
J Meyer, Elaine F. Harkness, Yit Yoong Lim, Susan M. Astley, Mary E. Wilson, Julie Morris, M Bydder, CE Mercer, Anthony J. Maxwell
Publikováno v:
Breast Cancer Research : BCR
Previous work has demonstrated that approximately 14% of women who attend their first breast screening appointment fail to attend the next appointment. It is well recognised that some women experience marked discomfort or pain during mammography whic
Publikováno v:
Breast Cancer Research : BCR
Introduction Over the last decade several breast cancer risk alleles have been identified which has led to an increased interest in individualised risk prediction for clinical purposes. Methods We investigate the performance of an up-to-date 18 breas
Autor:
Anthony J. Swerdlow, Alan Ashworth, James Griffin, Emily McFadden, Minouk J. Schoemaker, Michael Jones, Lauren B. Wright
Publikováno v:
Breast Cancer Research : BCR
Background Women diagnosed with breast cancer frequently attribute their cancer to psychological stress, but scientific evidence is inconclusive. We investigated whether experienced frequency of stress and adverse life events affect subsequent breast
Autor:
Kathleen Conway, Douglas A. Bell, Yu Li, Chiu-Kit Tse, Beth Newman, Robert C. Millikan, Lisa Cui
Publikováno v:
Breast Cancer Research
Introduction Epidemiologic studies have not shown a strong relationship between blood levels of polychlorinated biphenyls (PCBs) and breast cancer risk. However, two recent studies showed a stronger association among postmenopausal white women with t
Publikováno v:
Breast Cancer Research : BCR
Introduction Breast cancer comprises clinically distinct subtypes, but most risk statistics consider breast cancer only as a single entity. To estimate subtype-specific lifetime breast cancer risks, we took advantage of population-based data for whic
Publikováno v:
Breast Cancer Research
Introduction Much recent work has focused on hypotheses that very early life exposures influence adult cancer risk. For breast cancer it has been hypothesized that high in utero estrogen exposure may increase risk. Methods We used data from the Carol
Publikováno v:
Breast Cancer Research : BCR
Introduction Diabetes during pregnancy is related to enhanced fetal growth, which has been associated with increased breast cancer risk. Whether daughters of mothers with a diagnosis of diabetes have an increased risk of breast cancer is not known. M
Autor:
Hanna Birke, Anthony Howell, Adam R. Brentnall, Stephen W. Duffy, Jennifer Stone, Ruth Warren, Jack Cuzick, Elizabeth Pinney, Jane Warwick
Publikováno v:
Breast Cancer Research : BCR
Introduction Mammographic density is well-established as a risk factor for breast cancer, however, adjustment for age and body mass index (BMI) is vital to its clinical interpretation when assessing individual risk. In this paper we develop a model t