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Autor:
Long hua Zhao, Jian Fei Wang, Wanping Hu, Li Zhong, Jin Chi Zu, Xu Gao, Xiao Gang Zhang, Kun Ge, Kemp H. Kernstine, Wei Ke Shen, Yun Yen
Publikováno v:
Breast Cancer Research : BCR
Introduction Only a limited number of tumor markers for breast cancer are currently available. Antibodies to tumor-associated proteins may expand the number of available tumor markers for breast cancer and may be used together in a serum profile to e
Publikováno v:
Breast Cancer Research
Menopausal hormone therapy (HT) is typically withheld from breast cancer survivors because of concerns about risk for recurrence. Our objectives were to estimate the effects of HT on recurrence in breast cancer survivors and to examine the reliabilit
Autor:
Mario Giuliano, Emilia Montagna, Diego D'Agostino, Sabino De Placido, Giuseppe Cancello, Monica Plaitano, Giuseppe Di Lorenzo, Michele De Laurentiis, Antonio Giordano
Publikováno v:
Breast Cancer Research : BCR
INTRODUCTION: We performed a retrospective analysis of HER2-overexpressing metastatic breast cancer patients to describe clinical outcomes of those who, despite progression of the disease (PD), maintained trastuzumab for multiple chemotherapy lines.
Publikováno v:
Breast Cancer Research
Introduction Mammographic density is a strong, independent risk factor for breast cancer. A critical unanswered question is whether cancers tend to arise in mammographically dense tissue (i.e. are densities directly related to risk or are they simply
Autor:
Jinbo Chen, Michael Kalos, Joshua Bauml, Angela DeMichele, Susan Q. Li, Jun J. Mao, Jean D. Boyer, Lu Chen
Publikováno v:
Breast Cancer Research : BCR
Introduction Arthralgia is a common toxicity among women taking aromatase inhibitors (AIs) and can lead to premature discontinuation of therapy. We evaluated the association between arthralgia, co-morbid fatigue and/or insomnia, and inflammatory biom
Publikováno v:
Breast Cancer Research : BCR
Introduction Characterizing and differentiating between malignant tumors, benign tumors, and normal breast tissue is increasingly important in the patient presenting with breast problems. Near-infrared diffuse optical imaging and spectroscopy is capa
Autor:
Rochelle E. Curtis, Mark M. Huycke, Bassam Ghabach, William F. Anderson, Jackie A. Lavigne, Graça M. Dores
Publikováno v:
Breast Cancer Research : BCR
Introduction Adenoid cystic carcinoma of the breast (breast-ACC) is a rare and special type of basal-like tumor for which scant population-based descriptive data exist. We sought to provide new population-based information on breast-ACC incidence, re
Autor:
Stephanie A. Kennedy, Jennifer Gallagher, Lee G. Wilke, Marlee K. Junker, Nimmi Ramanujam, Torre Michelle Bydlon, Joseph Geradts, J. Quincy Brown, William T. Barry
Publikováno v:
Breast Cancer Research : BCR
Introduction Residual cancer following breast conserving surgery increases the risk of local recurrence and mortality. Margin assessment presents an unmet clinical need. Breast tissue is markedly heterogeneous, which makes distinguishing small foci o
Publikováno v:
Breast Cancer Research : BCR
There is variation in the literature and between breast units in the diffuse cortical thickening (DCT) threshold used for preoperative lymph node needle sampling. In our centre, needle sampling is performed in patients with DCT of 2 mm and above (LN3
Publikováno v:
Breast Cancer Research : BCR
Introduction Proteasome inhibition provides an attractive approach to cancer therapy and may have application in the treatment of breast cancer. However, results of recent clinical trials to evaluate the effect of the proteasome inhibitor Bortezomib