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Autor:
Fredrik Granath, Andor Pivarcsi, Clara Ibel Chamorro, Annelie Liljegren, Günther Weber, Romuald Mentaverri, Samuel Rotstein, Bengt Sandstedt, Zuzana Saidak, Fabio Sánchez, Mona Ståhle, Sami Zreika
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research
Breast Cancer Research, BioMed Central, 2009, pp.R6
Breast Cancer Research
Breast Cancer Research, BioMed Central, 2009, pp.R6
Introduction Human cathelicidin antimicrobial protein, hCAP18, and its C-terminal peptide LL-37 is a multifunctional protein. In addition to being important in antimicrobial defense, it induces chemotaxis, stimulates angiogenesis and promotes tissue
Autor:
Thilo Dörk, Douglas F. Easton, Paul D.P. Pharoah, Scarlett Reincke, Laura J. van't Veer, Flora E. van Leeuwen, Mitul Shah, Johanna Tommiska, Rainer Fagerholm, Manjeet K. Humphreys, Marjanka K. Schmidt, Annegien Broeks, Carl Blomqvist, Heli Nevanlinna
Publikováno v:
Breast Cancer Research : BCR
INTRODUCTION: Somatic inactivation of the TP53 gene in breast tumors is a marker for poor outcome, and breast cancer outcome might also be affected by germ-line variation in the TP53 gene or its regulators. We investigated the effects of the germ-lin
Publikováno v:
Breast Cancer Research
Breast Cancer Research, BioMed Central, 2004, 6 (3), pp.R252-63. ⟨10.1186/bcr784⟩
Breast Cancer Res
Breast Cancer Res, 2004, 6 (3), pp.R252-63. 〈10.1186/bcr784〉
Breast Cancer Research, 2004, 6 (3), pp.R252-63. ⟨10.1186/bcr784⟩
Breast Cancer Research, BioMed Central, 2004, 6 (3), pp.R252-63. ⟨10.1186/bcr784⟩
Breast Cancer Res
Breast Cancer Res, 2004, 6 (3), pp.R252-63. 〈10.1186/bcr784〉
Breast Cancer Research, 2004, 6 (3), pp.R252-63. ⟨10.1186/bcr784⟩
INTRODUCTION: Little is known of the function and clinical significance of intratumoral dysregulation of xenobiotic-metabolizing enzyme expression in breast cancer. One molecular mechanism proposed to explain tamoxifen resistance is altered tamoxifen
Autor:
Marguerite Ennis, Susan J. Done, David R. McCready, Ryan J.O. Dowling, Michael Reedijk, Martin C. Chang, Vuk Stambolic, Jaime Escallon, Pamela J. Goodwin, Wey L. Leong, Saroj Niraula
Publikováno v:
Breast Cancer Research : BCR
The antidiabetic drug metformin exhibits potential anticancer properties that are believed to involve both direct (insulin-independent) and indirect (insulin-dependent) actions. Direct effects are linked to activation of AMP-activated protein kinase
Autor:
Alexander Dobrovic, Stephen B. Fox, Ewan K.A. Millar, Sandra A O'Toole, Andreas Möller, Mira C.P. Liu, Christina S.F. Wong, Robert L. Sutherland, Katie T. Huang, Peter Chan, Catriona M. McNeil, David D.L. Bowtell, Nic Waddell, Jaclyn Sceneay
Publikováno v:
Breast Cancer Research : BCR
Introduction: The seven in absentia homolog 2 (SIAH2) protein plays a significant role in the hypoxic response by regulating the abundance of hypoxia-inducible factor-a; however, its role in breast carcinoma is unclear. We investigated the frequency
Autor:
Frédéric Fina, Caroline Bascoul-Mollevi, Anne-Claire Laberenne, L'Houcine Ouafik, William Jacot, Pierre-Jean Lamy, Pierre-Marie Martin
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research
Breast Cancer Research, BioMed Central, 2011, 13, pp.R15. ⟨10.1186/bcr2824⟩
Breast Cancer Research, vol. 13, no. 1, pp. R15
Breast Cancer Research
Breast Cancer Research, BioMed Central, 2011, 13, pp.R15. ⟨10.1186/bcr2824⟩
Breast Cancer Research, vol. 13, no. 1, pp. R15
International audience; Introduction: Human epidermal growth factor receptor 2 (HER2)-amplified breast cancers represent a tumor subtype with chromosome 17q rearrangements that lead to frequent gene amplifications. The aim of this study was to quanti