Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Katsunori Iwasaki"'
Autor:
Takuya Watanabe, Shutaro Katsurabayashi, Kenichi Mishima, Kotaro Takasaki, Kazunori Sano, Katsunori Iwasaki, Nobuaki Egashira, Kazuhide Hayakawa, Michihiro Fujiwara, Norito Yamagata
Publikováno v:
Brain Research. 1249:222-228
Acetylcholine (ACh) release is one of the key factors in memory mechanisms. To clarify whether beta-amyloid (Aβ) induces a disturbance of the cholinergic system leading to memory impairment, we examined memory impairment and measured hippocampal ACh
Autor:
Kazuhide Hayakawa, Takashi Egawa, Kenichi Mishima, Naoki Uchida, Michihiro Fujiwara, Keiichi Irie, Kazunori Sano, Katsunori Iwasaki, Mai Hazekawa, Ryoji Nishimura, Kensuke Orito, Yoshihisa Kitamura, Nobuaki Egashira
Publikováno v:
Brain Research. 1188:157-164
Cannabidiol, a non-psychoactive component of cannabis, has been reported to have interactions with Delta(9)-tetrahydrocannabinol (Delta(9)-THC). However, such interactions have not sufficiently been clear and may have important implications for under
Autor:
Tomomi Matsuda, Takuya Watanabe, Akihiko Takashima, Ryoji Nishimura, Katsunori Iwasaki, Nobuaki Egashira, Hideyuki Kawabe, Michihiro Fujiwara, Kenichi Mishima, Shozo Chidori
Publikováno v:
Brain Research. 1059:7-12
Mutant R406W human tau was originally identified in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) and causes a hereditary tauopathy that clinically resembles Alzheimer's disease (AD). In the current study, we examined the
Publikováno v:
Brain Research. 952:239-245
The purpose of this study was to identify brain sites that contribute to the delta(9)-tetrahydrocannabinol (delta(9)-THC)-induced impairment of spatial memory in rats. Rats were tested in the eight-arm radial maze after microinjections of delta(9)-TH
Publikováno v:
Brain Research. 769:287-295
Alzheimer's beta-amyloid peptide (A beta) is normally present at nanomolar concentrations in body fluids and in the medium of cultured cells. In vitro experiments have shown that A beta has neurotrophic effects and can promote neuronal adhesion and e
Autor:
Ryoji Nishimura, Michihiro Fujiwara, Tetsuya Naito, Naoki Uchida, Kanako Uchida, Ai Nogami, Kaori Kubota, Taro Shindo, Kenichi Mishima, Tamami Haraguchi, Kotaro Takasaki, Katsunori Iwasaki, Shutaro Katsurabayashi
Publikováno v:
Brain research. 1353
Telmisartan, an angiotensin type 1 receptor blocker (ARB), is used for hypertension to control blood pressure and has been shown to have a partial agonistic effect on peroxisome proliferator-activated receptor gamma (PPARgamma). Recently, the ligand
Publikováno v:
Brain Research. 583:227-236
The effects of non-competitive NMDA antagonists, MK-801 and dextrorphan in relation to the rise in intracellular Ca2+ concentrations ([Ca2+]i) after stimulation with 15 mM K+ in whole brain synaptosomes from young (3 months old) and aged (24 months o
Autor:
Michihiro Fujiwara, Ryoji Nishimura, Noriko Ishigami, Akiko Yano, Michihiko Matsushita, Masayuki Fujioka, Kenichi Mishima, Katsunori Iwasaki, Nobuaki Egashira
Publikováno v:
Brain research. 1069(1)
The purpose of this study was to identify mechanisms that mediate the impairment of spatial memory induced by 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), a 5-HT1A/5-HT7 receptor agonist, in the eight-arm radial maze in rats. WAY-100635 and NA
Publikováno v:
Brain research. 709(2)
We investigated the disruption of spatial cognition due to transient forebrain ischemia using an 8-arm radial arm maze task in rats. Five or 10 min of ischemia did not affect the task acquisition. When rats established spatial cognition by daily trai