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Author/Creator:
Marta Tkacz, Joanna Listos, Patrycja Kupnicka, Sylwia Talarek, Dariusz Chlubek, Irena Baranowska-Bosiacka, Katarzyna Barczak, Maciej Tarnowski, Izabela Gutowska, Emilia Metryka
Published in:
Brain Research. 1719:49-56
Morphine is one of the most potent analgesics used in medicine and it's long-term use is associated with the risk of the state of dependence. The cessation of chronic morphine administration leads to withdrawal signs which are associated with neurotr
Author/Creator:
Paola Lenzi, Rosangela Ferese, Francesca Biagioni, Michele Madonna, Fiona Limanaqi, Francesco Fornai, Stefano Gambardella
Published in:
Brain Research. 1719:157-175
Methamphetamine (Meth) produces a variety of epigenetic effects in the brain, which are seminal to establish long-lasting alterations in neuronal activity. However, most epigenetic changes were described by measuring the rough amount of either histon
Published in:
Brain Research. 1718:46-52
Objective The activation of renin angiotensin system is involved in multiple pathological processes. Growing evidence reveal that Angiotensin II (Ang II) contributes to the pathogenesis of Alzheimer disease (AD). However, the underlying mechanisms ar
Published in:
Brain research. 1766
Alzheimer’s disease (AD) is one of the greatest geriatric medicinal challenges of our century and is the main disease leading to dementia. Despite extensive scientific research advances, available disease-modifying treatment strategies remained lim
Author/Creator:
Xin Liu, Yuhan Li, Peiwen Guo, Hua Feng, Qiang Tan, Zhouyang Jiang, Zhi Chen, Jiru Zhou
Published in:
Brain Research. 1715:41-46
Arginine-vasopressin (AVP) is believed to be positively correlated with the brain edema formation, but the underlying mechanism is still unclear. In this study, we explored the role of the V2 receptors antagonist tolvaptan on brain edema following in
Author/Creator:
Brian C. Kaszuba, Paul J. Feustel, Julie G. Pilitsis, Ian Walling, Amelia Stapleton, Teresa Maietta, Damian S. Shin, Julia Slyer
Published in:
Brain Research. 1715:66-72
Chronic pain is the most common non-motor symptom among Parkinson’s disease (PD) patients, with 1.85 million estimated to be in debilitating pain by 2030. Subthalamic deep brain stimulation (STN DBS) programmed for treating PD motor symptoms has al
Author/Creator:
Bethany R. Brookshire, Gregory V. Carr, Falk W. Lohoff, Thomas N. Ferraro, Irwin Lucki
Published in:
Brain Research. 1712:151-157
The vesicular monoamine transporter is involved in presynaptic catecholamine storage and neurotransmission. Two isoforms of the transporter exist, VMAT1 and VMAT2, and both are expressed in the brain, though VMAT2 expression is more robust and has be
Published in:
Brain Res
Extrasynaptic glutamate within the nucleus accumbens is a driver of relapse. Cocaine, ethanol, and methamphetamine reduce the expression of cystine-glutamate antiporter (xCT) and primary glial glutamate transporter 1 (GLT1) leading to increased extra
Published in:
Brain Research. 1711:1-6
Hypotension and low cerebral perfusion pressure are associated with low cerebral blood flow, cerebral ischemia, and poor outcomes after traumatic brain injury (TBI). Cerebral autoregulation is impaired after TBI, contributing to poor outcome. In prio
Published in:
Brain Research. 1707:190-197
In Parkinson's disease (PD), α-synuclein (αSyn) accumulation and inclusion triggers dopamine neuronal death and synapse dysfunction in vivo. We previously reported that fatty acid-binding protein 3 (FABP3) is highly expressed in the brain and accel