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Autor:
Marta Tkacz, Joanna Listos, Patrycja Kupnicka, Sylwia Talarek, Dariusz Chlubek, Irena Baranowska-Bosiacka, Katarzyna Barczak, Maciej Tarnowski, Izabela Gutowska, Emilia Metryka
Publikováno v:
Brain Research. 1719:49-56
Morphine is one of the most potent analgesics used in medicine and it's long-term use is associated with the risk of the state of dependence. The cessation of chronic morphine administration leads to withdrawal signs which are associated with neurotr
Autor:
Paola Lenzi, Rosangela Ferese, Francesca Biagioni, Michele Madonna, Fiona Limanaqi, Francesco Fornai, Stefano Gambardella
Publikováno v:
Brain Research. 1719:157-175
Methamphetamine (Meth) produces a variety of epigenetic effects in the brain, which are seminal to establish long-lasting alterations in neuronal activity. However, most epigenetic changes were described by measuring the rough amount of either histon
Autor:
Ai-Mei Liao, Zi-Shan Zhang, Long Pan, Yong-Jian Yuan, Guanghai Yu, Jian Cao, Cui-Zhu Tian, Huang Jihong, Ming Hui, Yu-Qi Dong, Shuai-Nan Zheng, Wen-Jin Lin, Yin-Chen Hou, Xiaoxiao Li, Zeng-Liang Liu
Publikováno v:
Brain Research. 1773:147672
Wheat embryo globulin nutrient (WEGN), with wheat embryo globulin (WEG) as the main functional component, is a nutritional combination that specifically targets memory impairment. In this study, we explored the protective role of WEGN on Alzheimer's
Publikováno v:
Brain research. 1741
Melanin-concentrating hormone (MCH) is a neuropeptide primarily transcribed in the lateral hypothalamus (LH), with vast projections to many areas throughout the central nervous system that play an important role in motivated behaviors and drug use. A
Publikováno v:
Brain Research. 1670:14-23
Leptomycin B (LMB), originally developed as an anti-fungal agent, has potent neuroprotective properties against status epilepticus (SE, a prolonged seizure activity). However, the pharmacological profiles and mechanisms of LMB for neuroprotection rem
Publikováno v:
Brain Research. 1663:1-8
With the decline of ovarian steroids levels at menopause, many women experience an increase in anxiety and stress sensitivity. The locus coeruleus (LC), a central source of noradrenaline (NE), is activated by stress and is inhibited by β-endorphin.
Publikováno v:
Brain Research. 1659:148-155
Methamphetamine (METH) is a widely abused psychostimulant displaying potent addictive and neurotoxic properties. METH induces neurotoxicity of dopaminergic terminals and striatal neurons in the striatum. Despite much information on neurotransmitters,
Publikováno v:
Brain Research. 1646:551-559
The theta rhythm discovered in the posterior hypothalamus area (PHa) differs from theta observed in the hippocampal formation. In comparison to hippocampal spontaneous theta, the theta recorded in the PHa is rarely registered, has lower amplitude, of
Publikováno v:
Brain research. 1715
To investigate the mechanisms underlying the neuroprotective effect of tacrolimus (FK506) on the hippocampal neurons of rats with status epilepticus (SE).A total of 126 male Wistar rats were randomly and equally divided into the control group, the ep
Autor:
Teng-yue Zhang, Jing-jun Zheng, Zhao-Rui Wang, Mei Zhang, Xu Qian, Wei Li, Ji-qiang Ding, Jia-gui Zhong
Publikováno v:
Brain research. 1714
Temporal lobe epilepsy (TLE) is a chronic neurological disorder that is a refractory disease. Baicalein possesses various pharmacological activities, including neuroprotection in neurodegenerative disease. However, whether baicalein is protective in