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Autor:
Marta Tkacz, Joanna Listos, Patrycja Kupnicka, Sylwia Talarek, Dariusz Chlubek, Irena Baranowska-Bosiacka, Katarzyna Barczak, Maciej Tarnowski, Izabela Gutowska, Emilia Metryka
Publikováno v:
Brain Research. 1719:49-56
Morphine is one of the most potent analgesics used in medicine and it's long-term use is associated with the risk of the state of dependence. The cessation of chronic morphine administration leads to withdrawal signs which are associated with neurotr
Autor:
Paola Lenzi, Rosangela Ferese, Francesca Biagioni, Michele Madonna, Fiona Limanaqi, Francesco Fornai, Stefano Gambardella
Publikováno v:
Brain Research. 1719:157-175
Methamphetamine (Meth) produces a variety of epigenetic effects in the brain, which are seminal to establish long-lasting alterations in neuronal activity. However, most epigenetic changes were described by measuring the rough amount of either histon
Publikováno v:
Brain research. 1766
Alzheimer’s disease (AD) is one of the greatest geriatric medicinal challenges of our century and is the main disease leading to dementia. Despite extensive scientific research advances, available disease-modifying treatment strategies remained lim
Publikováno v:
Brain Research. 1715:41-46
Arginine-vasopressin (AVP) is believed to be positively correlated with the brain edema formation, but the underlying mechanism is still unclear. In this study, we explored the role of the V2 receptors antagonist tolvaptan on brain edema following in
Autor:
Brian C. Kaszuba, Paul J. Feustel, Julie G. Pilitsis, Ian Walling, Amelia Stapleton, Teresa Maietta, Damian S. Shin, Julia Slyer
Publikováno v:
Brain Research. 1715:66-72
Chronic pain is the most common non-motor symptom among Parkinson’s disease (PD) patients, with 1.85 million estimated to be in debilitating pain by 2030. Subthalamic deep brain stimulation (STN DBS) programmed for treating PD motor symptoms has al
Publikováno v:
Brain Research. 1712:151-157
The vesicular monoamine transporter is involved in presynaptic catecholamine storage and neurotransmission. Two isoforms of the transporter exist, VMAT1 and VMAT2, and both are expressed in the brain, though VMAT2 expression is more robust and has be
Publikováno v:
Brain Res
Extrasynaptic glutamate within the nucleus accumbens is a driver of relapse. Cocaine, ethanol, and methamphetamine reduce the expression of cystine-glutamate antiporter (xCT) and primary glial glutamate transporter 1 (GLT1) leading to increased extra
Publikováno v:
Brain Research. 1711:1-6
Hypotension and low cerebral perfusion pressure are associated with low cerebral blood flow, cerebral ischemia, and poor outcomes after traumatic brain injury (TBI). Cerebral autoregulation is impaired after TBI, contributing to poor outcome. In prio
Autor:
Burcu Üstüner, Gokcen Guvenc, Duygu Udum-Kucuksen, Elif Gokce, Begum Aydin, Burcin Altinbas, Murat Yalcin, Selim Alcay, Nasir Niaz, Mehmed Berk Toker
Publikováno v:
Brain Research. 1699:150-157
Brain histamine holds a key position in the regulation of behavioral states, biological rhythms, body weight, energy metabolism, thermoregulation, fluid balance, stress and reproduction in female animals. However, it is not clear whether central hist
Autor:
Weiping Wang, Lijing Jia, Huifang Cao, Zhenzhen Qu, Zhiyong Wang, Qian Hou, Lichao Zhang, Yuhang Jiang, Shuang Tian
Publikováno v:
Brain research. 1764
Status epilepticus (SE) is a neurological emergency. The pathological hallmark of neuronal damage after epileptic seizures could be the chain reaction of oxygen free radicals. Hydroxylated fullerenes (HFs) are novel and effective free radical scaveng