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Autor:
Jin Hee Kim, Hui Chul Choi, Song Hee Lee, Hong Ki Song, Bo Young Choi, Sang Won Suh, Dong Won Lee, Min Sohn
Publikováno v:
Brain Research. 1595:156-165
Citicoline (CDP-choline; cytidine 5'-diphosphocholine) is an important intermediate in the biosynthesis of cell membrane phospholipids. Citicoline serves as a choline donor in the biosynthetic pathways of acetylcholine and neuronal membrane phospholi
Autor:
Danielle C. Malkusz, Theodore Banakos, Trisha Dindyal, Vishal Vig, Richard J. Bodnar, Francis M. Rotella, Kerstin Olsson, Ira Yenko
Publikováno v:
Brain Research. 1596:116-125
Systemic dopamine (DA) D1 (SCH23390: SCH) and D2 (raclopride: RAC) antagonists blocked fructose-conditioned flavor preference (CFP) acquisition and expression. Fructose-CFP acquisition was eliminated by medial prefrontal cortex (mPFC) SCH and mPFC or
Autor:
Shuzhuo Zhang, Jin Li, Hui Wang, Lujia Yang, Yuelei Jin, Xiao-Yan Liu, Zhi juan Ge, Jianquan Zheng
Publikováno v:
Brain Research. 1582:1-11
Methamphetamine (METH) is a psychostimulant drug. Abuse of METH produces long-term behavioral changes including behavioral, sensitization, tolerance, and dependence. It induces neurotoxic effects in several areas of the brain via enhancing dopamine (
Publikováno v:
Brain Research. 1554:12-20
Extracellular acidosis is a common feature in pain-generating pathological conditions. Acid-sensing ion channels (ASICs), pH sensors, are distributed in peripheral sensory neurons and participate in nociception. Morphine exerts potent analgesic effec
Autor:
Danielle C. Malkusz, Richard J. Bodnar, Francis M. Rotella, Salomon Kandov, Nicole J. Amador, Anthony Sclafani, Sean M. Duenas, Khalid Touzani, Arzman Badalia, Julie A. Dela Cruz, Maruf Hossain, Meri Gerges, Sonia Y. Bernal
Publikováno v:
Brain Research. 1542:70-78
The attraction to sugar-rich foods is influenced by conditioned flavor preferences (CFP) produced by the sweet taste of sugar (flavor–flavor learning) and the sugar's post-oral actions (flavor–nutrient) learning. Brain dopamine (DA) circuits are
Publikováno v:
Brain Research. 1543:173-178
Leukocyte behavior in the cerebral microvasculature following vessel occlusion has not been fully elucidated. The purpose of this study was to investigate the effects of cilostazol on leukocyte behavior (rolling and adhesion) in murine cerebral micro
Autor:
Michihiro Igarashi, Kosuke Ando, Masami Takahashi, Ryoki Ishikawa, Kyota Aoyagi, Yoshihisa Kudo
Publikováno v:
Brain Research. 1535:1-13
The purpose of this study was to determine whether calmodulin (CaM) plays a role in neurotransmitter release by examining the effect that ophiobolin A (OBA), a CaM antagonist, on neurotransmitter release from clonal rat pheochromocytoma PC12 cells, p
Autor:
V. Visockis, Anne King
Publikováno v:
Brain Research. 1513:9-16
There is strong evidence that M-currents modulate peripheral sensory afferent excitability and that altered M-current efficacy may underpin aspects of pain-induced nociceptor sensitization. Less clear is the role of the M-current in regulating centra
Publikováno v:
Brain Research. 1510:48-62
Rats were trained in a two lever food reinforced operant procedure to discriminate a 8000 Hz pure tone stimulus from its absence. Responding on one lever was reinforced in the presence of the tone and responding on the other lever was reinforced when
Autor:
Nasim Sadat Pajohanfar, Akbar Pejhan, Bahareh Amin, Abolfazl Rad, Ehsan Mohebbi, Samad Nazemi
Publikováno v:
Brain research. 1657
Background In this study, we evaluated the effects of atorvastatin, a lipid-lowering medication on morphine-induced tolerance and dependence in mice. Methods Tolerance was induced by subcutaneous administration of morphine (20 mg/kg) to animals, twic