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Publikováno v:
Brain Research. 1712:151-157
The vesicular monoamine transporter is involved in presynaptic catecholamine storage and neurotransmission. Two isoforms of the transporter exist, VMAT1 and VMAT2, and both are expressed in the brain, though VMAT2 expression is more robust and has be
Publikováno v:
Brain Research. 1734:146759
Dopamine is the predominant catecholamine neurotransmitter in the mammalian brain which has been shown to play a critical role in antinociceptive process. Previous studies have shown that the role of CA1 region of the hippocampus in antinociception i
Autor:
Alberto Pinzon, Brian R. Noga
Publikováno v:
Brain Research. 1529:209-222
Catecholamine release was measured from bovine adrenal medullary chromaffin cell (CC) cultures maintained over a period of three months. Cells were plated over simple biocompatible cell platforms with electrical stimulation capability and at specifie
Publikováno v:
Brain Research. 1474:100-109
Parkinson's disease (PD) is a progressive neurodegenerative disorder which leads to the selective loss of dopaminergic neurons. This causes a decrease in the important neurotransmitter dopamine (DA), which is essential for coordinated movement. Previ
Publikováno v:
Brain Research. 1369:208-215
There is increasing evidence that traumatic brain injury (TBI) induces hypofunction of the striatal dopaminergic system, the mechanisms of which are unknown. In this study, we analyzed the activity of striatal tyrosine hydroxylase (TH) in rats at 1 d
Publikováno v:
Brain Research. 1349:48-55
Studies have demonstrated defects of DA and 5HT neurotransmission in dietary fat induced obese animals. In the present study, we used a perfusion system to assay the release of DA and 5HT from striatal slices preloaded with [(3)H]-DA or [(3)H]-5HT. T
Autor:
Caleb Carati, Katharine A. Brennan, Susan Schenk, Joyce Colussi-Mas, Rodney A. Lea, Paul S. Fitzmaurice
Publikováno v:
Brain Research. 1317:137-146
A number of studies have shown that exposure to high doses of methamphetamine (MA) is toxic to central dopamine (DA) and serotonin (5-HT) neurons. In most of those studies, however, high doses of MA were experimenter-administered during a short expos
Autor:
Roy A. Wise, Marisela Morales
Publikováno v:
Brain Research. 1314:38-43
Stress-induced reinstatement of cocaine-seeking is blocked by antagonists for the stress-related neurohormone corticotropin-releasing factor (CRF). One site of this action is the ventral tegmental area (VTA), where mild footshock stress causes CRF re
Publikováno v:
Brain Research. 1300:105-113
An isoindolin-1-one derivate, JM-1232(−), was recently developed as a sedative and hypnotic agent with a strong affinity for the central benzodiazepine binding site of gamma-aminobutyric acidA (GABAA) receptors. The purpose of this study was to exa
Autor:
Mohammad Yahiya Khan, Jayantee Kalita, Gautam Palit, Sandeep Kumar, Vinay K. Khanna, Usha K. Misra, Ausaf Ahmad
Publikováno v:
Brain Research. 1292:136-147
Japanese encephalitis (JE) is associated with a variety of movement disorders including transient form of pakinsonian features, dystonia and miscellaneous movement disorders. The neurotransmitters have important role in movement disorders. However th