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Publikováno v:
Brain Research. 1715:41-46
Arginine-vasopressin (AVP) is believed to be positively correlated with the brain edema formation, but the underlying mechanism is still unclear. In this study, we explored the role of the V2 receptors antagonist tolvaptan on brain edema following in
Publikováno v:
Brain Research. 1648:11-18
The systemic administration of opioids can be used for their strong analgesic effect. However, extensive activation of opioid receptors (ORs) beyond the targeted tissue can cause dysphoria, pruritus, and constipation. Therefore, selective activation
Autor:
Gyula Szabó, Péter Bokor, Beáta Balangó, Krisztina Csabafi, András Búzás, Gyula Telegdy, Miklos Palotai, Dávid Pintér, Zsolt Bagosi, Balázs Simon
Publikováno v:
Brain research. 1706
The aim of the present study was to investigate the participation of corticotropin-releasing factor (CRF) receptors (CRF1 and CRF2) in the alterations of the dorsal and ventral striatal dopamine release and the vertical and horizontal locomotor activ
Autor:
Bing Zhao, Wei-Ping Zhang, Qiao-Juan Shi, Dong-min Xu, Li Xiao, Er-Qing Wei, Yun-Bi Lu, Xiao-Ying Sa, Shu-Ying Yu, San-Hua Fang, Xia-Yan Zhang, Xiao-rong Wang
Publikováno v:
Brain Research. 1484:57-67
Cysteinyl leukotrienes (CysLTs) induce inflammatory responses by activating their receptors, CysLT 1 R and CysLT 2 R. We recently reported that CysLT 2 R is involved in neuronal injury, astrocytosis and microgliosis after focal cerebral ischemia in r
Publikováno v:
Brain Research. 1090:58-68
Apart from activation of the brain reward system, cocaine administration influences the activity of the hypothalamo-pituitary-adrenal (HPA) axis by affecting CRH neurons in the paraventricular nucleus of the hypothalamus (PVN). In order to find a mol
Publikováno v:
Brain Research. 1020:188-195
A large body of evidence supports the notion that Delta9-tetrahydrocannabinol (THC) stimulates food intake by its actions on CB1 cannabinoid receptors. Indirect evidence also suggests a role for dopamine (DA) receptors in mediating THC-induced feedin
Publikováno v:
Brain Research. 996:180-186
The multiple-day hyperphagic effect of the melanocortin 3/4 receptor antagonist, SHU9119, is apparently abolished when rats are food-deprived for 24 h after central (4th-ventricular) injection. Here, we affirmed this indication, and addressed the pos
Publikováno v:
Brain Research. 972:159-167
D(3) dopamine receptor agonists inhibit locomotor activity in rodents and modulate the reinforcing effect of psychostimulants; however, their functional role during behavioral sensitization remains unclear. In the present study, we intend to investig
Publikováno v:
Brain Research. 970:169-177
The inhibitory effect of the melatonin receptor antagonist luzindole on voltage-activated transient outward K(+) current (I(K(A))) was investigated in cultured rat cerebellar granule cells using the whole cell voltage-clamp technique. At the concentr
Autor:
Sara Kelly, Victoria Chapman
Publikováno v:
Brain Research. 935:103-108
Vanilloid VR1 receptors are located in the dorsal horn of the spinal cord. The aim of the present study was to determine the role of spinal vanilloid receptors (VR1) during nociceptive processing in control and inflamed rats. Effects of spinal admini