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Publikováno v:
Brain Research. 1689:109-122
Temporal lobe epilepsy (TLE) is a chronic neurological disease characterized by recurrent spontaneous seizures. MicroRNAs are dysregulated in various pathological conditions including epilepsy. Therefore, we hypothesized that the dysregulation of the
Publikováno v:
Brain research. 1707
Cognitive and memory impairment are related to cholinergic dysfunction and are important complications of viral encephalitis, In view of paucity of studies on cholinergic dysfunction in encephalitis, this study has been undertaken. We report acetyl c
Autor:
S. Van Huffel, R. Peeters, J. De Vocht, Stefan Sunaert, Uwe Himmelreich, Akila Weerasekera, P. Van Damme, Diana M. Sima, Tom Dresselaers, Kurt Claeys
Publikováno v:
Brain research. 1718
Previous MRI and proton spectroscopy (1H-MRS) studies have revealed impaired neuronal integrity and altered neurometabolite concentrations in the motor cortex of patients with amyotrophic lateral sclerosis (ALS). Here, we aim to use MRI with conventi
Autor:
Sang-Yoon Lee, Zang-Hee Cho, Young Don Son, Eun-Jung Choi, Young-Bo Kim, Yo-Han Joo, Jeong-Hee Kim, Jong-Hoon Kim
Publikováno v:
Brain Research. 1629:63-71
Self-transcendence is an inherent human personality trait relating to the experience of spiritual aspects of the self. We examined the relationship between self-transcendence and serotonin transporter (SERT) availability in brainstem raphe nuclei, wh
Publikováno v:
Brain Research. 1732:146589
Background Changes in peripheral blood amino acids have been noted in Relapse Remitting Multiple Sclerosis (RRMS), suggesting their potential diagnostic value in anticipating disease progression. Objective The present study sought to comprehensively
Publikováno v:
Brain Research. 1727:146559
Increasing the intensity of auditory stimuli has been shown to produce faster simple reaction times (RTs). Typical explanations for this effect involve earlier detection of the more intense stimulus; however, these explanations fail to consider how s
Publikováno v:
Brain research. 1701
The inhibitory neurotransmitter γ-aminobutyric acid (GABA) is known to be fundamental to the neuronal processes underlying visual orientation and vibrotactile frequency and amplitude discrimination. Previous studies have demonstrated that performanc
Publikováno v:
Brain research. 1704
Purpose To report oxidative stress in the patients with status epilepticus (SE), and correlate these with severity, MRI and outcome. Methods Thirty-five patients with SE and 34 controls were included. Blood sample was collected at admission for measu
Autor:
Guozheng Xu, Xiaohong Yin, Xiangyu Wang, Shun Li, Xiao-ping Tang, Jun Wen, Long Zhao, Kashif Rafiq Zahid, Xiangrong Chen, Jie Duan, Maoying Zhang, Liu Zhang, Jun-wei Duan, Yuanchuan Wang, Lifang Mao
Publikováno v:
Brain research. 1692
Histone deacetylase 1 (HDAC1) plays a crucial role in cancer progression and development. This enzyme has been confirmed to be a key regulator of tumor biology functions, such as tumor cell proliferation, migration and invasion. However, HDAC1 expres
Publikováno v:
Brain Research. 1556:57-66
Platelet-derived growth factor-B (PDGF-B) is a growth factor that regulates cell migration, proliferation, and differentiation, and is involved in several physical and pathological processes. The overexpression of PDGF-B in glioma surgical samples re