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Publikováno v:
Brain Research. 1646:551-559
The theta rhythm discovered in the posterior hypothalamus area (PHa) differs from theta observed in the hippocampal formation. In comparison to hippocampal spontaneous theta, the theta recorded in the PHa is rarely registered, has lower amplitude, of
Autor:
Xincai Ji, Gilles E. Martin
Publikováno v:
Brain Research. 1588:1-16
Dopamine, a key neurotransmitter mediating the rewarding properties of drugs of abuse, is widely believed to exert some of its effects by modulating neuronal activity of nucleus accumbens (NAcc) medium spiny neurons (MSNs). Although its effects on sy
Publikováno v:
Brain Research. 1554:12-20
Extracellular acidosis is a common feature in pain-generating pathological conditions. Acid-sensing ion channels (ASICs), pH sensors, are distributed in peripheral sensory neurons and participate in nociception. Morphine exerts potent analgesic effec
Autor:
V. Visockis, Anne King
Publikováno v:
Brain Research. 1513:9-16
There is strong evidence that M-currents modulate peripheral sensory afferent excitability and that altered M-current efficacy may underpin aspects of pain-induced nociceptor sensitization. Less clear is the role of the M-current in regulating centra
Autor:
Lourdes M. Nogueira, Antonieta Lavin
Publikováno v:
Brain Research. 1351:57-63
Among the brain structures involved in processing affective stimuli, the roles of the prefrontal cortex (PFC) and the mesocorticolimbic dopaminergic (DA) innervation are well established. In contrast to our understanding of the reward stimuli, less i
Autor:
Hans-Joachim Galla, José Luis Hernández Cáceres, Marc Häder, Ulrich Altrup, Michaela C. Meyer, Stefan Malcharek
Publikováno v:
Brain Research. 1122:65-77
Mechanisms of epileptiform activity in a model nervous system (buccal ganglia of Helix pomatia) are presented. The ganglia contain the identified giant neurons B1 through B4. For epileptiform activity, pentylenetetrazol (1 mmol/L to 40 mmol/L) or eto
Autor:
George V. Rebec, James J. Cortright
Publikováno v:
Brain Research. 1092:108-116
The striatum, which receives projections from the entire cortical mantle, is highly responsive to sensorimotor activity. Because either systemic or intra-striatal injections of ascorbate (AA) influence behavior known to involve striatal circuits, it
Autor:
J. Victor Nadler, Olga Timofeeva
Publikováno v:
Brain Research. 1078:227-234
Recurrent mossy fiber synapses in the dentate gyrus of epileptic brain facilitate the synchronous firing of granule cells and may promote seizure propagation. Mossy fiber terminals contain and release zinc. Released zinc inhibits the activation of NM
Autor:
Marian H. Lewandowski, Tomasz Błasiak
Publikováno v:
Brain Research. 1009:82-87
The intergeniculate leaflet of the thalamus is, besides the suprachiasmatic nucleus of the hypothalamus, the other important neuronal element of the mammalian biological clock. The extracellularly recorded activity of neurons constituting the interge
Publikováno v:
Brain Research. 1007:160-166
We have demonstrated recently that the quail brain possesses the cholesterol side-chain cleavage enzyme (cytochrome P450scc) and 3beta-hydroxysteroid dehydrogenase/Delta(5)-Delta(4)-isomerase (3beta-HSD) and produces pregnenolone, pregnenolone sulfat