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Publikováno v:
Brain Research. 1719:30-39
Schizophrenia is known to be a complex and disabling psychiatric disorder. Dopamine receptor antagonists have a significant therapeutic effect in improving the positive symptoms that are associated with the illness. Therefore, dopamine receptor antag
Publikováno v:
Brain Res
Alzheimer’s dementia is the leading cause of dementia in older adults and women are disproportionately burdened. It is increasingly recognized that dementia in older persons is related to the co-occurrence of mixed pathologies in the brain, but few
Autor:
Marta Tkacz, Joanna Listos, Patrycja Kupnicka, Sylwia Talarek, Dariusz Chlubek, Irena Baranowska-Bosiacka, Katarzyna Barczak, Maciej Tarnowski, Izabela Gutowska, Emilia Metryka
Publikováno v:
Brain Research. 1719:49-56
Morphine is one of the most potent analgesics used in medicine and it's long-term use is associated with the risk of the state of dependence. The cessation of chronic morphine administration leads to withdrawal signs which are associated with neurotr
Publikováno v:
Brain Res
The dense expression of glucocorticoid receptors (GR) within the amygdala, medial prefrontal cortex (mPFC) and paraventricular nucleus of hypothalamus (PVN) mediates many aspects of emotional and stress regulation. Importantly, both prenatal alcohol
Autor:
Kevin De Pauw, Douglas M. Jones, Steve Folger, Stephen P Bailey, Bart Roelands, Romain Meeusen, Michael J. Buono
Publikováno v:
Brain Research. 1718:1-9
Exposure to cold causes disturbances in cognitive performance that can have a profound impact on the safety, performance, and success of populations that frequent cold environments. It has recently been suggested that repeated cold stress, resulting
Autor:
Weiguang Zhang, Juan Sun, Renyu Liu, Yan Zhang, Jianfei Lu, Xiaomei Yang, Changman Zhou, Chunhua Chen, Qin Hu
Publikováno v:
Brain Research. 1719:64-70
Early brain injury (EBI) refers to the direct injury to the brain during the first 72 h after subarachnoid hemorrhage (SAH), which is one of the major causes for the poor clinical outcome after SAH. In this study, we investigated the effect and the r
Autor:
Qing-Jie Xia, Qiao Hu, Jia Liu, Ya Jiang, You-Cui Wang, Zheng Ma, Lu-Lu Xue, Ying Zhang, Liu-Lin Xiong, Yuan Jin, Yang-Yang Wang, Ting-Hua Wang
Publikováno v:
Brain Research. 1719:77-88
Neonatal hypoxic-ischemic encephalopathy (HIE) always results in severe neurologic dysfunction, nevertheless effective treatments are limited and the underlying mechanism also remains unclear. In this study, we firstly established the neonatal HIE mo
Autor:
Robert H. Rosenwasser, Michael J. Lang, Richard F. Schmidt, Ruihe Lin, Thana Theofanis, Ashwini Sharan, Geoffrey Stricsek, Lorraine Iacovitti, Aurore Lebrun, D. Craig Hooper
Publikováno v:
Brain Research. 1718:231-241
The sphenopalatine ganglion (SPG) is a vasoactive mediator of the anterior intracranial circulation in mammals. SPG stimulation has been demonstrated to alter blood-brain barrier (BBB) permeability, although this phenomenon is not well characterized.
Autor:
Nayna Sanathara, Olivier Civelli, Lamees Alhassen, Alice Lo, Wedad Alhassen, Paul Nguyen, Amal Alachkar, Alvin Phan, Hanan Shaharuddin
Publikováno v:
Brain Research. 1719:71-76
Melanin concentrating hormone (MCH) is involved in the initiation of maternal behavior during the postpartum period. Virgin females also display some aspects of maternal care independent of the hormonal and neurochemical changes associated with pregn
Autor:
Paola Lenzi, Rosangela Ferese, Francesca Biagioni, Michele Madonna, Fiona Limanaqi, Francesco Fornai, Stefano Gambardella
Publikováno v:
Brain Research. 1719:157-175
Methamphetamine (Meth) produces a variety of epigenetic effects in the brain, which are seminal to establish long-lasting alterations in neuronal activity. However, most epigenetic changes were described by measuring the rough amount of either histon