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Autor:
Marta Tkacz, Joanna Listos, Patrycja Kupnicka, Sylwia Talarek, Dariusz Chlubek, Irena Baranowska-Bosiacka, Katarzyna Barczak, Maciej Tarnowski, Izabela Gutowska, Emilia Metryka
Publikováno v:
Brain Research. 1719:49-56
Morphine is one of the most potent analgesics used in medicine and it's long-term use is associated with the risk of the state of dependence. The cessation of chronic morphine administration leads to withdrawal signs which are associated with neurotr
Publikováno v:
Brain Research. 1715:27-34
The aim of the present study was to determine the involvement of the VTA 5-HT1A receptors in analgesia induced by the co-administration of morphine and dextromethorphan (DM). Male Wistar rats were bilaterally cannulated in the VTA by the stereotaxic
Publikováno v:
Brain Research. 1715:41-46
Arginine-vasopressin (AVP) is believed to be positively correlated with the brain edema formation, but the underlying mechanism is still unclear. In this study, we explored the role of the V2 receptors antagonist tolvaptan on brain edema following in
Autor:
Xuezhu Cai, Jochen C. Hartner, Barbara L. Waszczak, Praveen Kulkarni, Dan Madularu, Sade Iriah, Tatiana M. Knox, Tom Morrison, Craig F. Ferris, Ju Qiao
Publikováno v:
Brain Research. 1706:58-67
Parkinson's Disease (PD) is the second most common neurodegenerative disorder, with 60,000 new cases diagnosed each year in the US. There are multiple animal models of PD that attempt to mimic the effects of the disease through genetic alteration. Co
Publikováno v:
Brain Research. 1702:3-11
Building upon the knowledge that a number of important brain circuits undergo significant degeneration in Alzheimer's disease, numerous recent studies suggest that the norepinephrine-ergic system in the brainstem undergoes significant alterations ear
Publikováno v:
Brain Research. 1698:195-203
This study investigated the therapeutic effect of hippocampal low-frequency stimulation (Hip-LFS) and its influence on the type A γ-aminobutyric acid receptor α1 subunit (GABAA R α1 subunit), inducible cAMP early repressor (ICER) and brain-derived
Autor:
Teiji Tominaga, Mika Sato-Maeda, Hidenori Endo, Shuntaro Ikawa, Ahmed Mansour, Sherif Rashad, Miki Fujimura, Kuniyasu Niizuma
Publikováno v:
Brain Research. 1699:54-68
Cerebral venous thrombosis (CVT) is a rare form of cerebral stroke that causes a variety of symptoms, ranging from mild headache to severe morbidity or death in the more severe forms. The use of anti-coagulant or thrombolytic agents is the classical
Autor:
Ping Lei, Jianning Zhang, Fanglian Chen, Xin Xu, Zhenyu Yin, Haichen Wang, Xiaodong Kong, Shan Huang, Xintong Ge, Wenzhu Li
Publikováno v:
Brain Research. 1697:10-20
Pyroptosis is a highly specific type of inflammatory programmed cell death that different from necrosis or apoptosis. It is initiated by cellular detection of acute damage via recognizing pathogen-associated molecular patterns (PAMPs) by NOD-like rec
Publikováno v:
Brain research. 1756
The episodic nature of chronic pain can be studied in the rodent model of latent pain sensitization. After remission, central sensitization is opposed by activation of opioid receptors. At the behavioral level, latent pain sensitization is unmasked w
Autor:
Iana V. Gorina, Anatoly Chernykh, Yulia K. Komleva, Anton N. Shuvaev, Olga L. Lopatina, Alla B. Salmina, Ilia V. Potapenko
Publikováno v:
Brain research. 1752
Neuroinflammation has been classified as a trigger of behavioral alterations and cognitive impairments in many neurological conditions, including Alzheimer's disease, major depression, anxiety and others. Regardless of the cause of neuroinflammation,