Zobrazeno 1 - 10
of 360
pro vyhledávání: ''
Autor:
Jing-Da Qiao, Wen-Jun Bian, Yan-Hui Chen, Rong-Na Ren, Na He, Mi Jiang, Jie Wang, Xiao-Rong Liu, Yi Wu, Si-Mei Lin, Yu-Xi Liu, Tao Su, Yan Sun, Bin Li, Zhen Mei, Wei-Ping Liao, Yi-Wu Shi, De-Tian Liu, Yu Jing, Wei-Yue Gu, Bing-Mei Li, Yong-Hong Yi, Han-Kui Liu
Publikováno v:
Brain
The unc-13 homolog B (UNC13B) gene encodes a presynaptic protein, mammalian uncoordinated 13-2 (Munc13-2), which is highly expressed in the brain—predominantly in the cerebral cortex—and plays an essential role in synaptic vesicle priming and fus
Autor:
Qiao Wei, Dian-Fu Chen, Yin Ma, Hong-Fu Li, Zhi-Ying Wu, Hao Yu, Ge Bai, Hai-Lin Dong, Lei Chen, Jia-Qi Li, Gong-Lu Liu
Publikováno v:
Brain : a journal of neurology. 144(8)
Sensory neuronopathies are a rare and distinct subgroup of peripheral neuropathies, characterized by degeneration of the dorsal root ganglia neurons. About 50% of sensory neuronopathies are idiopathic and genetic causes remain to be clarified. Throug
Autor:
Anita Shankar, Adeen Flinker, Simon Henin, Daniel Friedman, Anli Liu, Werner Doyle, Orrin Devinsky, György Buzsáki, Helen Borges
Publikováno v:
Brain
We describe the spatiotemporal course of cortical high-gamma activity (HGA), hippocampal ripple activity and interictal epileptiform discharges (IEDs) during an associative memory task in 15 epilepsy patients undergoing invasive electroencephalograph
Autor:
Katsutaka Yonezawa, Hidenori Suzuki, Takashi Sakai, Masahito Kawaguchi, Satoshi Nozawa, Daisaku Takeuchi, Fumio Hasue, Michiko Hanawa, Masaya Mimura, Takayuki Fujiyoshi, Yukei Matsumoto, Taro Matsumoto, Jun Shimbo, Koji Akeda, Michiharu Matsuda, Haruo Kanno, Masashi Yamazaki, Yohei Kawasaki, Hiroshi Takahashi, Masahiko Watanabe, Daisuke Togawa, Chizuo Iwai, Toshihiko Taguchi, Daisuke Soma, Kazuyoshi Nakanishi, Norio Kawahara, Yukihiro Matsuyama, Futoshi Asano, Yasushi Ijima, Hiroyuki Katoh, Tomoyuki Takigawa, Go Yoshida, Tomohiro Matsumoto, Tomohiko Hasegawa, Toshimitsu Eto, Toru Hirano, Satoshi Inami, Ko Hashimoto, Koshiro Kamiya, Yoshihito Ozawa, Tetsuya Abe, Masahito Yoshioka, Masao Koda, Kan Takase, Naosuke Kamei, Yugo Orita, Sumio Ikenoue, Shin Oe, Hiroshi Moridaira, Kei Watanabe, Sho Kobayashi, Yu Yamato, Hideyuki Arima, Hideki Hanaoka, Ikuo Aita, Yasuaki Imajo, Takuya Morita, Hideo Baba, Shinji Kotaka, Yukio Someya, Junya Saito, Masafumi Fujii, Yosuke Takeuchi, Takeshi Sasamoto, Tatsuki Mizouchi, Masayuki Ohashi, Norihiro Nishida, Yoshito Katayama, Takayuki Yamaguchi, Mitsuhiro Kitamura, Kazunari Fushimi, Tadami Fujiwara, Tsuyoshi Okudaira, Takuya Miyamoto, Fumitake Nakajima, Yoshikazu Ikeda, Haruki Ueda, Hirokazu Shoji, Yasuhisa Fujii, Seiji Ohtori, Tsukasa Kanchiku, Akihiro Sudo, Yosuke Shibao, Toshimi Aizawa, Masahiro Funaba, Hiroshi Imai, Takeshi Kikuchi, Takehiro Sugaya, Takeo Furuya, Keigo Ito, Eiji Kawamoto, Nobuhiro Tanaka, Hiroshi Taneichi, Mitsuhiro Hashimoto, Yasuo Ito, Hiroaki Sameda, Hiroaki Konishi, Toshihiko Sakakibara
Publikováno v:
Brain
Attenuation of the secondary injury of spinal cord injury (SCI) can suppress the spread of spinal cord tissue damage, possibly resulting in spinal cord sparing that can improve functional prognoses. Granulocyte colony-stimulating factor (G-CSF) is a
Autor:
Mark Wilson, David J. Sharp, Amy Jolly, Mohammad Mahmud, Elena Calzolari, Barry M. Seemungal, Mariya Chepisheva, Rebecca G. Smith, Heiko Rust, Qadeer Arshad, Vassilios Tahtis, Peter J. Hellyer
Publikováno v:
Brain
Calzolari et al. show that acute traumatic brain injury may cause a ‘vestibular agnosia’. This mediates imbalance both directly via white matter tract damage in the right temporal lobe, and indirectly by reducing clinician recognition of common,
Publikováno v:
Brain
Autor:
Yura Grabovska, Nitin R. Wadhwani, Renee Read, Dolores Hambardzumyan, Cameron Herting, James Ross, Tobey J. MacDonald, Frank Szulzewsky, Jeffrey M. Switchenko, Lenore Monterroza, Patrick J. Cimino, Alan Mackay, Chris Jones, Zhihong Chen, Montserrat Puigdelloses, Matthew Schniederjan, Oren J. Becher
Publikováno v:
Brain
Paediatric high-grade gliomas (HGGs) account for the most brain tumour-related deaths in children and have a median survival of 12–15 months. One promising avenue of research is the development of novel therapies targeting the properties of non-neo
Autor:
Antoinette Gelot, Alexis Brice, Agnès Camuzat, Benoit Rucheton, Laureen Chat, Dario Saracino, Frédérique Fluchère, Johannes Alexander Lobrinus, Fabienne Clot, Sylvie Forlani, Peter Myers, Alexandra Durr, Ludmila Jornea, Isabelle Le Ber, Vincent Huin, Foudil Lamari, Mathieu Barbier, Armand Bottani, Catherine Caillaud, Stéphane Auvin, Charles Duyckaerts
Publikováno v:
Brain, Vol. 143, No 1 (2020) pp. 303-319
Brain-A Journal of Neurology
Brain-A Journal of Neurology, Oxford University Press (OUP), 2020, 143 (1), pp.303-319. ⟨10.1093/brain/awz377⟩
Brain-A Journal of Neurology, 2020, 143 (1), pp.303-319. ⟨10.1093/brain/awz377⟩
Brain-A Journal of Neurology
Brain-A Journal of Neurology, Oxford University Press (OUP), 2020, 143 (1), pp.303-319. ⟨10.1093/brain/awz377⟩
Brain-A Journal of Neurology, 2020, 143 (1), pp.303-319. ⟨10.1093/brain/awz377⟩
Homozygous mutations in the progranulin gene (GRN) are associated with neuronal ceroid lipofuscinosis 11 (CLN11), a rare lysosomal-storage disorder characterized by cerebellar ataxia, seizures, retinitis pigmentosa, and cognitive disorders, usually b
Autor:
Yoshihisa Takiyama, Stefanie Brock, Jennifer Hirst, Niklas Dahl, Radka Kremlikova Pourova, Andrea Martinuzzi, Seth Perlman, Helene Verhelst, Omnia Fathy El-Rashidy, Nour Elkhateeb, Sarah I. Sheikh, Jamal Ghoumid, Erin Carmody, Georgia Xiromerisiou, Diego Miguel, James T. Bennett, Barbara Brechmann, William O. Walker, David Dacruz-Álvarez, Mathieu Anheim, Dana M. Jensen, Stefan Kölker, Uzma Shamshad, Darius Ebrahimi-Fakhari, Grace Yoon, Katharina Vill, David Bearden, Adel A. Mahmoud, Sheela Nampoothiri, Devorah Segal, Antje Wiesener, Shenela Lakhani, Joseph G. Gleeson, Chirag Patel, Angelica D'Amore, Abdelrahim Abdrabou Sadek, Marvin Ziegler, Mustafa Sahin, Toni S. Pearson, Julian Teinert, Kira A. Dies, Christopher J. Yuskaitis, Catherine L. Salussolia, Lubov Blumkin, Jonathan Baets, Laura Robelin, Daniel Ebrahimi-Fakhari, Parham Habibzadeh, Anju Shukla, Peter O. Bauer, Saskia Bulk, Afshin Saffari, Elizabeth Lim-Melia, Michael C. Kruer, Christian Beetz, Andreas Ziegler, Pankaj B. Agrawal, Thomas Bourinaris, Filippo M. Santorelli, Mireille Guillot, Abdullah Alamri, Mohammad Ali Faghihi, Kathrin Eberhardt, Thomas Smol, Henry Houlden, Nur Aydinli, Constanze Heine, Soroor Inaloo, Anaita Udwadia-Hegde, Alejandro Brea-Fernández, Yasemin Alanay, Rachana Dubey Gupta, Ayse Aksoy, Agathe Roubertie, Jens Volkmann, Basil T. Darras, Hendrik Langen, Mauricio R. Delgado, Jan Ulrich Schlump, Gregory Geisel, Anna Jansen, Somayeh Bakhtiari, Steven P. Miller, Miriam Wimmer, Maha S. Zaki, Premsai Nagabhyrava, Robert Behne, Hossein Darvish
Publikováno v:
Brain
Bi-allelic loss-of-function variants in genes that encode subunits of the adaptor protein complex 4 (AP-4) lead to prototypical yet poorly understood forms of childhood-onset and complex hereditary spastic paraplegia: SPG47 (AP4B1), SPG50 (AP4M1), SP
Autor:
Qiang Guo, Rui Zhao, Zhang Hua, Liping Zou, Weidong Yang, Ming Ge, Ping Ding, Tao Yu, Shaohui Zhang, Zhiquan Yang, Xu Wang, Jiong Qin, Chun-Qing Zhang, Yanwu Guo, Chen Lei, Guangming Zhang, Yunlin Li, Rui Zhang, Mei-Hua Yang, Wenling Li, Ruobing Qian, Fang Fang, Juncheng Zhang, Kai Zhang, Yuanxiang Lin, Qingzhu Liu, Xinwei Zhang, Shi-Yong Liu, Zhiqi Mao, Jian Yin, Yi Yao, Shuli Liang, Shan Yongzhi, Liu Yuan, Hong Tian, Yuguang Guan
Publikováno v:
Brain : a journal of neurology. 143(2)
At least 50% of patients with tuberous sclerosis complex present with intractable epilepsy; for these patients, resective surgery is a treatment option. Here, we report a nationwide multicentre retrospective study and analyse the long-term seizure an