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Autor:
Keld Danø, Hans Jørgen Nielsen, Jan Grøndahl-Hansen, F. Moesgaard, Nils Brünner, Ib Jarle Christensen, Ole Thorlacius-Ussing, Helle Pappot
Publikováno v:
Nielsen, H J, Pappot, H, Christensen, I J, Brünner, N, Thorlacius-Ussing, O, Moesgaard, F, Danø, K & Grøndahl-Hansen, J 1998, ' Association between plasma concentrations of plasminogen activator inhibitor-1 and survival in patients with colorectal cancer ', B M J-Clinical Research Edition, vol. 316, no. 7134, pp. 829-30 .
Editorial by Verspaget Invasion by cancer cells requires proteases such as the serine protease plasmin to degrade the cellular matrix. Plasmin is formed from its zymogen, plasminogen, a reaction catalysed by urokinase type plasminogen activator—whi