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Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background LncRNA DLGAP1-AS2 plays an oncogenic role in glioma, while its role in other cancers is unknown. This study aimed to study the role of DLGAP1-AS2 in non-small cell lung cancer (NSCLC). Methods Expression of DLGAP1-AS2 in NSCLC and paired n
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Chronic obstructive pulmonary disease (COPD) is a disease that causes obstructed airways and abnormal inflammatory responses in the lungs. Early growth response 3 (EGR3) has been revealed to play a vital role in the regulation of the infla
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Lung adenocarcinoma (LUAD) is one of the most common cancers with high morbidity and mortality worldwide. Long non-coding RNAs (lncRNAs) serve as tumor promoters or suppressors in the development of various human malignancies, including LU
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Sepsis is a complicated disease with systemic inflammation or organ dysfunction, and it is the leading cause of acute lung injury (ALI). Long non-coding RNAs (lncRNAs) have played important roles in the pathogenesis of sepsis. This study w
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background The echinoderm microtubule-associated protein-like-4 anaplastic lymphoma kinase (EML4-ALK) fusion gene was identified in a subset of non-small cell lung cancer (NSCLC) patients. They responded positively to ALK inhibitors. This study aimed
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-5 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background The identification of NTRK fusions in tumours has become critically important due to the actionable events predictive of response to TRK inhibitor. It is not clear whether the NTRK breakpoint location is different for response to targeted
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background To detect and investigate the expression of POU domain class 2 transcription factor 2 (POU2F2) in human lung cancer tissues, its role in lung cancer progression, and the potential mechanisms. Methods Immunohistochemical (IHC) assays were c
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-6 (2020)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background LncRNA SNHG10 has been reported to be an oncogenic lncRNA in liver cancer. However, its roles in non-small cell lung cancer (NSCLC) remains unknown. Methods Tumor and paired non-tumor tissues were harvested from 62 NSCLC patients. RT-qPCR
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Lung adenocarcinoma (LAD) is a prevalent type of bronchogenic malignant tumor and one of the most critical factors related to human death. Long noncoding RNAs (lncRNAs) are involved in many complex biological processes and have been emerge
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Introduction Long noncoding RNAs (lncRNAs) have been associated with many types of cancers, but their molecular mechanisms in lung squamous cell carcinoma (LUSC) have not been fully studied. Therefore, the current study investigated the regulation ro