Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nora Franceschini"'
Autor:
Kari E. North, Xia Li, Nora Franceschini, Juan M. Peralta, Harald H H Göring, Hao Li, Thomas D. Dyer, Mary K. Wojczynski
Publikováno v:
BMC Proceedings, Vol 1, Iss Suppl 1, p S85 (2007)
BMC Proceedings
BMC Proceedings
In order to identify regulatory genes, we determined the heritability of gene transcripts, performed linkage analysis to identify quantitative trait loci (QTLs), and evaluated the evidence for shared genetic effects among transcripts with co-localize
Publikováno v:
BMC Proceedings
BMC Proceedings, Vol 3, Iss Suppl 7, p S87 (2009)
BMC Proceedings, Vol 3, Iss Suppl 7, p S87 (2009)
Age-dependent genetic effects on susceptibility to hypertension have been documented. We present a novel variance-component method for the estimation of age-dependent genetic effects on longitudinal systolic blood pressure using 57,827 Affymetrix sin
Publikováno v:
BMC Proceedings
BMC Proceedings, Vol 3, Iss Suppl 7, p S118 (2009)
BMC Proceedings, Vol 3, Iss Suppl 7, p S118 (2009)
In order to evaluate the population impact of putative causal genetic variants over the life course of disease, we extended the static estimation of population-attributable risk fraction and developed a novel tool to evaluate how the population impac
Autor:
Christy L. Avery, Amanda A. Seyerle, Kristin L. Young, Kari E. North, Mariaelisa Graff, Shelly Ann Love, Jeffrey R. O'Connell, Anne E. Justice, Nora Franceschini, Chani J. Hodonsky, Lindsay Fernández-Rhodes, Geetha Chittoor, Annie Green Howard, V. Saroja Voruganti
Publikováno v:
BMC Proceedings
Background Nearly half of adults in the United States who are diagnosed with hypertension use blood-pressure-lowering medications. Yet there is a large interindividual variability in the response to these medications. Two complementary gene–environ
Autor:
Nora Franceschini, Jeffrey R. O'Connell, Guoqing Diao, V. Saroja Voruganti, Lindsay Fernández-Rhodes, Shelly Ann Love, Anne E. Justice, Christy L. Avery, Kristin L. Young, Misa Graff, Annie Green Howard, Kari E. North, Geetha Chittoor
Publikováno v:
BMC Proceedings
Background There is great interindividual variation in systolic blood pressure (SBP) as a result of the influences of several factors, including sex, ancestry, smoking status, medication use, and, especially, age. The majority of genetic studies have