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Autor:
Alemseged Beyene Berha, Workineh Shibeshi, Anandi N. Sheth, Getnet Yimer, Addisu Admasu, Zenebe Negash
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-10 (2019)
BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-10 (2019)
Background Nephrotoxicity and ototoxicity are clinically significant dose-related adverse effects associated with second-line anti-tubercular injectables drugs (aminoglycosides and capreomycin) used during intensive phase of treatment of multi-drug r
Autor:
Todd Bell, Roger Bedimo, Sara D. Brouse, Krystal K. Haase, Christopher R. Frei, Ronald G. Hall, Nicolas A. Forcade, Kathleen A. Hazlewood, Christopher Giuliano, Carlos A. Alvarez
Publikováno v:
BMC Pharmacology & Toxicology
Background Previous studies have established a correlation between vancomycin troughs and nephrotoxicity. However, data are currently lacking regarding the effect of guideline-recommended weight-based dosing on nephrotoxicity in methicillin-resistant
Autor:
Milica Stojiljković, Marko Stojanovic, Radmila Jankovic, Miroslav Radenković, Mirko Topalović
Publikováno v:
BMC Pharmacology & Toxicology
Background It is well established that diabetes mellitus represents an important risk factor for endothelial dysfunction and associated cardiovascular events. Accordingly, vascular responsiveness of different isolated blood vessels was shown to be al
Autor:
Milica Paut Kusturica, Bojan Stanimirov, Nebojša Pavlović, M. Stojancevic, Ana Sabo, Karmen Stankov, Momir Mikov
Publikováno v:
BMC Pharmacology & Toxicology
Results The overall consumption of medicines from A02B subgroup in 2010 in Serbia was 22.9 DID, whereas in Croatia and Sweden was 32.8 DID and 48.6 DID, respectively. In Serbia, H2RAs accounted for 71.8% (16.5 DID) of medicines used within A02B subgr
Autor:
Milica Atanacković, Radmila Novakovic, Vladimir Kanjuh, Jelena Cvejić, Dragana Protić, Ljiljana Gojkovic-Bukarica
Publikováno v:
BMC Pharmacology & Toxicology
Results Resveratrol relaxed RA of normal rats more potently than RA of rats with diabetes (EC50 8 and 50 μM, respectively). L-NAME and methylene blue partly antagonized the relaxation of RA of normal animals only. A nonselective blocker of voltage-g