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Autor:
Laurent Briollais, Yuanyuan Wang, Julia A. Knight, Ellen Shi, Isaac Rajendram, Venus Onay, Hilmi Ozcelik
Publikováno v:
BMC Medicine
BMC Medicine, Vol 5, Iss 1, p 22 (2007)
BMC Medicine, Vol 5, Iss 1, p 22 (2007)
Background There is growing evidence that gene-gene interactions are ubiquitous in determining the susceptibility to common human diseases. The investigation of such gene-gene interactions presents new statistical challenges for studies with relative
Publikováno v:
BMC medicine, 13
BMC Medicine
BMC Medicine
Age at breast cancer diagnosis is a known prognostic factor. Previously, several groups including ours have shown that young age at diagnosis is associated with higher prevalence of basal-like tumors and aggressive tumor phenotypes. Yet the impact of