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Autor:
Michel de Lorgeril, Patricia Salen
Publikováno v:
BMC Medicine
Background Physical exercise and healthy dietary habits are recommended to prevent breast cancer. Discussion Increased intake of omega-3 fatty acids associated with decreased omega-6 - resulting in higher omega-3 to omega-6 ratio compared with Wester
Autor:
Laurent Briollais, Yuanyuan Wang, Julia A. Knight, Ellen Shi, Isaac Rajendram, Venus Onay, Hilmi Ozcelik
Publikováno v:
BMC Medicine
BMC Medicine, Vol 5, Iss 1, p 22 (2007)
BMC Medicine, Vol 5, Iss 1, p 22 (2007)
Background There is growing evidence that gene-gene interactions are ubiquitous in determining the susceptibility to common human diseases. The investigation of such gene-gene interactions presents new statistical challenges for studies with relative
Autor:
Sileny Han, Frédéric Amant, Kristel Van Calsteren, Mina Mhallem Gziri, Anouk Lotgerink, Myriam Hanssens
Publikováno v:
BMC Medicine
BMC Medicine, Vol. 10, no.1, p. 86 (2012)
BMC Medicine, Vol 10, Iss 1, p 86 (2012)
BMC Medicine, Vol. 10, no.1, p. 86 (2012)
BMC Medicine, Vol 10, Iss 1, p 86 (2012)
Background Recent insights provide support for the treatment of cancer during pregnancy, a coincidence that poses both mother and fetus at risk. Our aim was to critically review studies on the physiologic variations during pregnancy, the most common
Autor:
Judy Garber, Luca Livraghi
Publikováno v:
BMC Medicine
Poly(ADP-ribose) polymerases (PARP) are enzymes involved in DNA-damage repair. Inhibition of PARPs is a promising strategy for targeting cancers with defective DNA-damage repair, including BRCA1 and BRCA2 mutation-associated breast and ovarian cancer
Autor:
Victor G. Vogel
Publikováno v:
BMC Medicine
Selective estrogen receptor modulators (SERMs) reduce the risk of recurrence of invasive breast cancer and the incidence of first breast cancers in women who are at increased risk. Multiple, randomized clinical trials have shown both the efficacy and
Autor:
Elena Provenzano, Helena M. Earl, Anne-Laure Vallier, Jean Abraham, Ioannis Gounaris, Louise Hiller, Janet A. Dunn
Publikováno v:
BMC Medicine
Background:\ud Neoadjuvant breast cancer trials are important for speeding up the introduction of new treatments for patients with early breast cancer and for the highly productive translational research which they facilitate. Meta-analysis of trial
Publikováno v:
BMC medicine, 13
BMC Medicine
BMC Medicine
Age at breast cancer diagnosis is a known prognostic factor. Previously, several groups including ours have shown that young age at diagnosis is associated with higher prevalence of basal-like tumors and aggressive tumor phenotypes. Yet the impact of
Autor:
Carlos Caldas
Publikováno v:
BMC Medicine
In this video Q&A, we talk to Professor Carlos Caldas about the identification of breast cancer subtypes through molecular profiling, and the clinical implications for diagnosis and treatment.