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Autor:
Dagnija Kalniete, Jekaterina Zestkova, Arvids Irmejs, Janis Gardovskis, Karina Aksenoka, Andris Gardovskis, Dace Berzina, Miki Nakazawa-Miklasevica, Edvins Miklasevics
Publikováno v:
BMC Medical Genetics
Background The estimated ratio of hereditary breast/ovarian cancer (HBOC) based on family history is 1.5% in Latvia. This is significantly lower than the European average of 5–10%. Molecular markers like mutations and SNPs can help distinguish HBOC
Autor:
Janez Zgajnar, Jacques De Greve, Guido Goelen, Erik Teugels, Mateja Krajc, Srdjan Novaković, Nikola Besic, Marko Hočevar
Publikováno v:
BMC Medical Genetics, Vol 9, Iss 1, p 83 (2008)
Vrije Universiteit Brussel
BMC Medical Genetics
Vrije Universiteit Brussel
BMC Medical Genetics
Background Both recurrent and population specific mutations have been found in different areas of the world and more specifically in ethnically defined or isolated populations. The population of Slovenia has over several centuries undergone limited m
Publikováno v:
BMC Medical Genetics
BMC Medical Genetics, Vol 13, Iss 1, p 41 (2012)
BMC Medical Genetics, Vol 13, Iss 1, p 41 (2012)
Background To date, evaluation of the association of the ABO blood group and breast cancer has yielded mixed results. SNP rs505922, located within the first intron of the ABO gene, has been associated with the adenocarcinoma subtype of pancreatic can
Autor:
Sakineh Abbasi
Publikováno v:
BMC Medical Genetics, Vol 11, Iss 1, p 109 (2010)
BMC Medical Genetics
BMC Medical Genetics
ER-alpha and ER-beta genes have been proven to play a significant role in breast cancer. Epidemiologic studies have revealed that age-incidence patterns of breast cancer in Middle East differ from those in the Western countries. Two selected coding r
Autor:
Eglė Šepetauskienė, Elona Juozaitytė, Darius Čereškevičius, Roberta Jankauskaitė, Aistė Savukaitytė, Rasa Ugenskienė
Publikováno v:
BMC Medical Genetics
Background Breast cancer is the most frequent oncological disease among women. Estrogens are known to play an important role in breast cancer development. Recognition of the relationship between polymorphisms within estrogen metabolizing genes and co
Autor:
Nicholas Eriksson, Amy K. Kiefer, Uta Francke, David A. Hinds, Geoffrey M Benton, Joyce Y. Tung, Joanna L. Mountain, Chuong B. Do
Publikováno v:
BMC Medical Genetics, Vol 13, Iss 1, p 53 (2012)
BMC Medical Genetics
BMC Medical Genetics
Background While some factors of breast morphology, such as density, are directly implicated in breast cancer, the relationship between breast size and cancer is less clear. Breast size is moderately heritable, yet the genetic variants leading to dif
Autor:
Daniel Levy, Bernard E. Kreger, Greta Lee Splansky, Carol L. Rosenberg, Joanne M. Murabito, Daniel Finger, Karen H. Antman, Shih-Jen Hwang
Publikováno v:
BMC Medical Genetics
Breast and prostate cancer are two commonly diagnosed cancers in the United States. Prior work suggests that cancer causing genes and cancer susceptibility genes can be identified. We conducted a genome-wide association study (Affymetrix 100K SNP Gen