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Autor:
Tim M J Ewoldt, Suzanne Polinder, T. van Gelder, Birgit C. P. Koch, Anouk E. Muller, Henrik Endeman, Nicole G. M. Hunfeld, Alan Abdulla, W. J.R. Rietdijk
Publikováno v:
BMC Infectious Diseases, 20(1). BioMed Central Ltd.
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Infectious Diseases
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Infectious Diseases
Background Critically ill patients undergo extensive physiological alterations that will have impact on antibiotic pharmacokinetics. Up to 60% of intensive care unit (ICU) patients meet the pharmacodynamic targets of beta-lactam antibiotics, with onl