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Autor:
Lotfi Chouchane, Erchin Serpedin, Chifeng Ma, Yi Chen, Yufei Huang, Yusheng Feng, Salah Gehani, Mario Flore, Issam Al-Bozom, Konduru S Sastry
Publikováno v:
BMC Genomics
Background We considered the prediction of cancer classes (e.g. subtypes) using patient gene expression profiles that contain both systematic and condition-specific biases when compared with the training reference dataset. The conventional normalizat
Autor:
Huanming Yang, Ramneek Gupta, José M.A. Moreira, Nils Brünner, Mathilde Borg Houlberg Thomsen, Yong Hou, Lars Bolund, Xiuqing Zhang, Henrik J. Ditzel, Anne-Sofie Schrohl, Rikke Linnemann Nielsen, Xun Xu, Jun Wang, Dongbing Liu, Stine Ninel Hansen, Jan Stenvang, Natasja Ehlers, Shida Zhu, Guangbiao Wang
Publikováno v:
BMC Genomics
Hansen, S N, Ehlers, N S, Zhu, S, Thomsen, M B H, Nielsen, R L, Liu, D, Wang, G, Hou, Y, Zhang, X, Xu, X, Bolund, L, Yang, H, Wang, J, Moreira, J, Ditzel, H J, Brünner, N, Schrohl, A-S, Stenvang, J & Gupta, R 2016, ' The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells ', BMC Genomics, vol. 17, 442 . https://doi.org/10.1186/s12864-016-2749-4
Hansen, S N, Ehlers, N S, Zhu, S, Thomsen, M B H, Nielsen, R L, Liu, D, Wang, G, Hou, Y, Zhang, X, Xu, X, Bolund, L, Yang, H, Wang, J, Moreira, J, Ditzel, H J, Brünner, N, Rasmussen, A-S S, Stenvang, J & Gupta, R 2016, ' The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells ', B M C Genomics, vol. 17, 442 . https://doi.org/10.1186/s12864-016-2749-4
Hansen, S N, Ehlers, N S, Zhu, S, Thomsen, M B H, Nielsen, R L, Liu, D, Wang, G, Hou, Y, Zhang, X, Xu, X, Bolund, L, Yang, H, Wang, J, Moreira, J, Ditzel, H J, Brünner, N, Schrohl, A-S, Stenvang, J & Gupta, R 2016, ' The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells ', B M C Genomics, vol. 17, no. 1, pp. 442 . https://doi.org/10.1186/s12864-016-2749-4
Hansen, S N, Ehlers, N S, Zhu, S, Thomsen, M B H, Nielsen, R L, Liu, D, Wang, G, Hou, Y, Zhang, X, Xu, X, Bolund, L, Yang, H, Wang, J, Moreira, J, Ditzel, H J, Brünner, N, Schrohl, A-S, Stenvang, J & Gupta, R 2016, ' The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells ', BMC Genomics, vol. 17, 442 . https://doi.org/10.1186/s12864-016-2749-4
Hansen, S N, Ehlers, N S, Zhu, S, Thomsen, M B H, Nielsen, R L, Liu, D, Wang, G, Hou, Y, Zhang, X, Xu, X, Bolund, L, Yang, H, Wang, J, Moreira, J, Ditzel, H J, Brünner, N, Rasmussen, A-S S, Stenvang, J & Gupta, R 2016, ' The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells ', B M C Genomics, vol. 17, 442 . https://doi.org/10.1186/s12864-016-2749-4
Hansen, S N, Ehlers, N S, Zhu, S, Thomsen, M B H, Nielsen, R L, Liu, D, Wang, G, Hou, Y, Zhang, X, Xu, X, Bolund, L, Yang, H, Wang, J, Moreira, J, Ditzel, H J, Brünner, N, Schrohl, A-S, Stenvang, J & Gupta, R 2016, ' The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells ', B M C Genomics, vol. 17, no. 1, pp. 442 . https://doi.org/10.1186/s12864-016-2749-4
Background: Resistance to taxane-based therapy in breast cancer patients is a major clinical problem that may be addressed through insight of the genomic alterations leading to taxane resistance in breast cancer cells. In the current study we used wh
Autor:
Jhih Rong Lin, Zhengdong D. Zhang, Ying Cai, Cristina Montagna, Kelly O'Brien, Quanwei Zhang, Rubén Nogales-Cadenas, Wen Zhang
Publikováno v:
BMC Genomics
Background Malignant breast cancer with complex molecular mechanisms of progression and metastasis remains a leading cause of death in women. To improve diagnosis and drug development, it is critical to identify panels of genes and molecular pathways
Autor:
John R. Mackey, Preethi Krishnan, Sambasivarao Damaraju, Kathryn Graham, Ashok Narasimhan, Olga Kovalchuk, Bo Wang, Dongping Li, Richard Berendt, Sunita Ghosh
Publikováno v:
BMC Genomics
Background Prognostication of Breast Cancer (BC) relies largely on traditional clinical factors and biomarkers such as hormone or growth factor receptors. Due to their suboptimal specificities, it is challenging to accurately identify the subset of p
Autor:
Francesca M. Buffa, David R. Mole, Ashwag Albukhari, Carme Camps, Syed Haider, Spyros Oikonomopoulos, Ioannis Ragousis, Peter J. Ratcliffe, Johannes Schödel, Hani Choudhry, Adrian L. Harris, Daniela Moralli
Publikováno v:
BMC Genomics
Transcriptional responses to hypoxia are central to the pathogenesis of many types of cancer. Today, pan-genome analyses of hypoxia have focused on protein-coding genes, however, the role of non-coding RNAs, in particular long non-coding RNAs (lncRNA
Autor:
Jake Y. Chen, Fan Zhang
Publikováno v:
BMC Genomics
Background Breast cancer is worldwide the second most common type of cancer after lung cancer. Plasma proteome profiling may have a higher chance to identify protein changes between plasma samples such as normal and breast cancer tissues. Breast canc
Publikováno v:
BMC Genomics
Background Breast cancer is a genetically heterogeneous type of cancer that belongs to the most prevalent types with a high mortality rate. Treatment and prognosis of breast cancer would profit largely from a correct classification and identification
Publikováno v:
BMC Genomics, Vol 11, Iss Suppl 1, p S9 (2010)
BMC Genomics
BMC Genomics
Background A sense-antisense gene pair (SAGP) is a gene pair where two oppositely transcribed genes share a common nucleotide sequence region. In eukaryotic genomes, SAGPs can be organized in complex sense-antisense architectures (CSAGAs) in which at
Autor:
Vikram B. Wali, Sophia N. Ononye, Weiwei Shi, Lajos Pusztai, René Natowicz, Tingting Jiang, Christos Hatzis, Yuval Kluger
Publikováno v:
BMC Genomics
BMC Genomics, BioMed Central, 2014, 15 (1), pp.876
BMC Genomics, BioMed Central, 2014, 15 (1), pp.876. ⟨10.1186/1471-2164-15-876⟩
BMC Genomics, BioMed Central, 2014, 15 (1), pp.876
BMC Genomics, BioMed Central, 2014, 15 (1), pp.876. ⟨10.1186/1471-2164-15-876⟩
Background Molecular heterogeneity of tumors suggests the presence of multiple different subclones that may limit response to targeted therapies and contribute to acquisition of drug resistance, but its quantification has remained challenging. Result
Autor:
Ana Osorio, Juan Manuel Rosa-Rosa, Emilio González, Olga M. Sinilnikova, Henry T. Lynch, Javier Benitez, Guillermo Pita, Peter Devilee, Melissa C. Southey, Anna González-Neira, David E. Goldgar, Christi J. van Asperen, Nicoline Hoogerbrugge, Rogier A. Oldenburg
Publikováno v:
BMC Genomics
BMC Genomics, Vol 8, Iss 1, p 299 (2007)
BMC Genomics, Vol 8, Iss 1, p 299 (2007)
Background The recent development of new high-throughput technologies for SNP genotyping has opened the possibility of taking a genome-wide linkage approach to the search for new candidate genes involved in heredity diseases. The two major breast can