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Publikováno v:
BMC Cancer. 22
Background Cancer is a major public health problem with pharmacotherapy being the cornerstone of its management. Cancer patients receive multiple drugs concurrently risking Drug-Drug Interactions (DDIs). DDIs, though avoidable, can significantly cont
Autor:
Min Deng, Jia-Bao Lin, Rong-Ce Zhao, Shao-Hua Li, Wen-Ping Lin, Jing-Wen Zou, Wei Wei, Rong-Ping Guo
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Cancer
BMC Cancer
Background The accuracy of existing biomarkers for predicting the prognosis of hepatocellular carcinoma (HCC) is not satisfactory. It is necessary to explore biomarkers that can accurately predict the prognosis of HCC. Methods In this study, original
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Cancer
BMC Cancer
Background Lymph node metastasis (LNM) status is an important prognostic factor that strongly influences the treatment decision of early gastric cancer (EGC). This study aimed to evaluate the pattern and clinical significance of LNM in EGC. Methods A
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Cancer
BMC Cancer
Background Malignant pleural mesothelioma (MPM) is a rare but fatal cancer, which is largely caused by exposure to asbestos. Reliable information about the incidence of MPM prior the influence of asbestos is lacking. The nationwide regional incidence
Autor:
Tong Liu, Hanping Shi, Youcheng Zhang, Qi Zhang, Kang-Ping Zhang, Wenqiang Li, Siqing Liu, Meng-Meng Song, Sarah Tan Siyin
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Cancer
BMC Cancer
Background Previous studies have observed a close association between hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) as well as extrahepatic cancers. However, research concerning the effect of HBV infection on the risk of colore
Autor:
Xiaoyu Wang, Xian Zhang, Linzhi Gao, Xiaoya Luo, Jun Lyu, Dong Zhang, Xuesong Gao, Yuan Shen, Shaolie Zheng, Guifang Jiang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer
BMC Cancer
Purpose Aims to compare the prognostic performance of the number of positive lymph nodes (PLNN), lymph node ratio (LNR) and log odds of metastatic lymph nodes (LODDS) and establish a prognostic nomogram to predict overall survival (OS) rate for patie
Autor:
Kenji Tamura, Kazuki Sudo, Hiroshi Yoshida, Takayuki Kinoshita, Tatsunori Shimoi, Kan Yonemori, Jun Hashimoto, Takahiro Fukuda, Yasuhiro Fujiwara, Masayuki Yoshida, Mayu Yunokawa, Chikako Shimizu, Akihiko Shimomura, Emi Noguchi, Tomoyasu Kato
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Cancer
BMC Cancer
Background The V-Akt murine thymoma viral oncogene (AKT) 1 (E17K) is a subfamily of serine/threonine protein kinases that affects the survival, proliferation, and invasion of cancer cells. The clinicopathological features and frequencies in Asian pop
Autor:
Fumitaka Kikkawa, Takayuki Murao, Shunichi Ishihara, Dai Okazaki, Yoshiyuki Itoh, Kaoru Uchiyama, Takeshi Kodaira, Takahiro Yamaguchi, Taro Murai, Yuuki Takase, Shinji Naganawa, Mariko Kawamura, Mika Mizuno, Yuta Shibamoto, Yutaro Koide
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Background Standard treatments for small cell carcinoma of the cervix (SCCC) have not been established. In this study, we aimed to estimate the optimal treatment strategy for SCCC. Methods This was a multicenter retrospective study. Medical records o
Autor:
Masahiro Tanji, Tomoko Shofuda, Susumu Miyamoto, Yoshiki Arakawa, Ema Yoshioka, Sachiko Minamiguchi, Yasuhide Makino, Masayuki Mano, Takeshi Kawauchi, Takanori Hirose, Masahiro Nonaka, Yohei Mineharu, Yoshiko Okita, Daisuke Kanematsu, Yoshinori Kodama, Yonehiro Kanemura
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
BMC Cancer
BMC Cancer
Background Mutations in driver genes such as IDH and BRAF have been identified in gliomas. Meanwhile, dysregulations in the p53, RB1, and MAPK and/or PI3K pathways are involved in the molecular pathogenesis of glioblastoma. RAS family genes activate
Autor:
Pariyada Tanjak, Somsri Laiteerapong, Panudeth Juengwiwattanakitti, Benjarat Thiengtrong, Nutchavadee Vorasan, Bhoom Suktitipat, Vitoon Chinswangwatanakul, Suwanit Therasakvichya, Cholticha Songjang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Background The situation of patients developing multiple primary cancers is becoming more frequent and graver. This study investigated the risks of developing second primary cancers that are related to first primary cancers, and the interval times of