Zobrazeno 51 - 60
of 288
pro vyhledávání: ''
The potential prognostic value of connexin 26 and 46 expression in neoadjuvant-treated breast cancer
Autor:
Tibor Krenács, Zsuzsanna Varga, Cosima Riemenschnitter, Janina Kulka, Cornelia Leo, Barna Wichmann, Ivett Teleki, Holger Moch, Marcell A Szász, Bärbel Papassotiropoulos
Publikováno v:
BMC Cancer, Vol 13, Iss 1, p 50 (2013)
BMC Cancer
BMC Cancer
Background Several classification systems are available to assess pathological response to neoadjuvant chemotherapy in breast cancer, but reliable biomarkers to predict the efficiency of primary systemic therapy (PST) are still missing. Deregulation
Autor:
Julie Von Behren, Theresa H.M. Keegan, Scarlett Lin Gomez, Lawrence H. Kushi, Candyce H. Kroenke, Marilyn L. Kwan, Peggy Reynolds, Salma Shariff-Marco
Publikováno v:
BMC Cancer
BMC cancer, vol 15, iss 1
BMC cancer, vol 15, iss 1
Background Integrated health care delivery systems, with their comprehensive and integrated electronic medical records (EMR), are well-poised to conduct research that leverages the detailed clinical data within the EMRs. However, information regardin
Publikováno v:
BMC Cancer
Background Histologically similar tumors even from the same anatomical position may still show high variability at molecular level hindering analysis of genome-wide data. Leveling the analysis to a gene regulatory network instead of focusing on singl
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 380 (2012)
BMC Cancer
BMC Cancer
Background Tumor development is known to be a stepwise process involving dynamic changes that affect cellular integrity and cellular behavior. This complex interaction between genomic organization and gene, as well as protein expression is not yet fu
Autor:
Michael Baumann, Arnoud J. Templeton, Beat Thürlimann, Thomas Ruhstaller, Sarah Stoll, Madeleine Schwizer, Michael Mark, Daniel Dietrich
Publikováno v:
BMC Cancer
Background Besides conventional adjuvant therapies, many breast cancer survivors engage in various activities like exercise, diet and complementary and alternative medicine (CAM) in order to improve their prognosis. Little is known about specific int
Autor:
Robert E. Ferrell, Joseph M. Zmuda, Emmanuel E. O. Uche, Lewis H. Kuller, Seymour Garte, Michael N. Okobia, Emanuela Taioli, Clareann H. Bunker, Stanley N.C. Anyanwu, Emmanuel Ezeome
Publikováno v:
BMC Cancer
BMC Cancer, Vol 8, Iss 1, p 338 (2008)
BMC Cancer, Vol 8, Iss 1, p 338 (2008)
Background Leptin, a 16 kDa polypeptide hormone, implicated in various physiological processes, exerts its action through the leptin receptor, a member of the class I cytokine receptor family. Both leptin and leptin receptor have recently been implic
Autor:
Maria A. Loizidou, Panayiotis Papadopoulos, Andreas Hadjisavvas, Rena Papachristoforou, Eleni Kakouri, Simon Malas, Maria Daniel, Kyriacos Kyriacou, Yiola Marcou, Thalia Michael, Nicos Middleton
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 447 (2010)
BMC Cancer
BMC Cancer
Background Breast cancer is the most common form of malignancy affecting women worldwide. It is also the leading cancer in females in Cyprus, with approximately 400 new cases diagnosed annually. It is well recognized that genetic variation as well as
Autor:
Like Qu, Caiyun Liu, Jianping Guo, Li Min, Chengchao Shou, Xiaofan Li, Yihao Li, Hua Yuan, Cheng Zhang, Ruolan Ma, Ruxuan Chen
Publikováno v:
BMC Cancer
Background Although radiotherapy following mastectomy was demonstrated to reduce the recurring risk and improve the prognosis of patients with breast cancer, it is also notorious for comprehensive side effects, hence only a selected group of patients
Autor:
Berit M. Pfitzner, Christoph Thomssen, Roland Moll, Silvia Darb-Esfahani, Sibylle Loibl, Gabriele Kaltenecker, Keyur Mehta, Bettina Fiedler, Carsten Denkert, Bernhard Högel, Beyhan Ataseven, Klaus Baumann, Holger Eidtmann, Thomas Rüdiger, Manfred Dietel, K Kittel, Gunter von Minckwitz
Publikováno v:
BMC Cancer
Background Gross cystic disease fluid protein 15 (GCDFP-15), which is regulated by the androgen receptor (AR), is a diagnostic marker for mammary differentiation in histopathology. We determined the expression of GCDFP-15 in breast cancer subtypes, i
Autor:
Gerson Shigeaki Hamada, Juvenal Motola, Shoichiro Tsugane, Motoki Iwasaki, Solange Maria Torchia Carvalho, Fábio Martins Laginha, Enbo Ma, Inês Nobuko Nishimoto, Ishihara Junko
Publikováno v:
BMC Cancer, Vol 9, Iss 1, p 122 (2009)
BMC Cancer
BMC Cancer
BackgroundSeveral studies have determined that dietary intake of B vitamins may be associated with breast cancer risk as a result of interactions between5,10-methylenetetrahydrofolate reductase (MTHFR)andmethionine synthase(MTR) in the one-carbon met