Zobrazeno 21 - 30
of 288
pro vyhledávání: ''
Publikováno v:
BMC Cancer
Background Although mammary microcalcification is frequently observed and has been associated with poor survival in patients with breast cancer, the genesis of calcification remains unclear. Carbonic anhydrase I (CA1) has been shown to promote calcif
Publikováno v:
BMC Cancer
Background Monoclonal antibodies have been used to effectively treat various tumors. We previously established a unique strategy to identify tumor specific antibodies by capturing B-cell response against breast tumor antigens from patient-derived sen
Publikováno v:
BMC Cancer
Background This analysis was undertaken to evaluate the practice patterns of Japanese physicians regarding curative-intent chemotherapy, especially in outpatient settings, and to define factors negatively affecting the maintenance of relative dose in
Autor:
Jan G. Hengstler, Marco Johannes Battista, D. Boehm, Susanne Gebhard, Antje Lebrecht, Marcus Schmidt, Christine Solbach, W. Siggelkow, Heinz Koelbl, Cristina Cadenas, Rosemarie Marchan, Birte Hellwig, Jörg Rahnenführer, Isabel Sicking, M. Gehrmann
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 562 (2012)
BMC Cancer
BMC Cancer
Background Inhibitors targeting the cell cycle-regulated aurora kinase A (AURKA) are currently being developed. Here, we examine the prognostic impact of AURKA in node-negative breast cancer patients without adjuvant systemic therapy (n = 766). Metho
Autor:
Adrienne Morey, Diana J. Hastrich, David Ingram, Peter C. Willsher, Arlene Chan, Belinda Brown
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 555 (2012)
BMC Cancer
BMC Cancer
Background Overall survival of HER2 positive metastatic breast cancer patients has been significantly improved with inclusion of trastuzumab to chemotherapy. Several studies have demonstrated discordant HER2 status in the primary and metastatic tumou
Autor:
Montserrat Rue, Roger Pla, Misericòrdia Carles, J. A. Espinàs, Ester Vilaprinyo, Pilar Brugulat, Montserrat Martínez-Alonso
Publikováno v:
BMC Cancer
Recercat. Dipósit de la Recerca de Catalunya
instname
Repositorio Abierto de la UdL
Universitad de Lleida
Dipòsit Digital de la UB
Universidad de Barcelona
ResearcherID
BMC Cancer, Vol 8, Iss 1, p 336 (2008)
Recercat. Dipósit de la Recerca de Catalunya
instname
Repositorio Abierto de la UdL
Universitad de Lleida
Dipòsit Digital de la UB
Universidad de Barcelona
ResearcherID
BMC Cancer, Vol 8, Iss 1, p 336 (2008)
Background In Catalonia (Spain) breast cancer mortality has declined since the beginning of the 1990s. The dissemination of early detection by mammography and the introduction of adjuvant treatments are among the possible causes of this decrease, and
Autor:
Birgitte Bruun Rasmussen, Anne Katrine Duun-Henriksen, Sarah Larsen, Anne Vibeke Lænkholm, Christina Westmose Yde, Martin Bak, Anne E. Lykkesfeldt, Tove Kirkegaard
Publikováno v:
Larsen, S L, Yde, C W, Laenkholm, A-V, Rasmussen, B B, Duun-Henriksen, A K, Bak, M, Lykkesfeldt, A E & Kirkegaard, T 2015, ' Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer ', B M C Cancer, vol. 15, 239 . https://doi.org/10.1186/s12885-015-1210-4
BMC Cancer
BMC Cancer
BACKGROUND: Resistance to antiestrogen therapy is a major clinical challenge in the treatment of estrogen receptor α (ER)-positive breast cancer. The aim of the study was to explore the growth promoting pathways of antiestrogen resistant breast canc
Publikováno v:
BMC Cancer
Background Dermatomyositis is an autoimmune myopathy characterized by proximal muscle weakness, muscle inflammation, and typical skin findings. It is a rare disease with an incidence of ~1/100 000. About 15–30 % of adult-onset cases are caused by u
Autor:
Michela Tebaldi, Valentina Zampiga, Dino Amadori, Wainer Zoli, Fabio Falcini, Gianluca Tedaldi, Rita Danesi, Daniele Calistri, Lucia Bedei
Publikováno v:
BMC Cancer
Background CHEK2 is a multi-cancer susceptibility gene whose common germline mutations are known to contribute to the risk of developing breast and prostate cancer. Case presentation Here, we describe an Italian family with a high number of cases of
Autor:
Christian F. Singer, Dietmar Pils, Dan Tong, Andrea Wolf, Margaretha Rudas, Gerda Hofstetter, Ingrid Schiebel, Nicole Concin, Georg Heinze, Robert Zeillinger
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 682 (2010)
BMC Cancer
BMC Cancer
Background Gene expression of peripheral myelin protein 22 (PMP22) and the epithelial membrane proteins (EMPs) was found to be differentially expressed in invasive and non-invasive breast cell lines in a previous study. We want to evaluate the progno