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Autor:
Qingwei Luo, Roberta De Angelis, Nehmat Houssami, Dianne L. O'Connell, Xue Qin Yu, Clare Kahn
Publikováno v:
BMC Cancer
Background Breast cancer places a heavy burden on the Australian healthcare system, but information about the actual number of women living with breast cancer and their current or future health service needs is limited. We used existing population-ba
Autor:
Adrienne Morey, Diana J. Hastrich, David Ingram, Peter C. Willsher, Arlene Chan, Belinda Brown
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 555 (2012)
BMC Cancer
BMC Cancer
Background Overall survival of HER2 positive metastatic breast cancer patients has been significantly improved with inclusion of trastuzumab to chemotherapy. Several studies have demonstrated discordant HER2 status in the primary and metastatic tumou
Autor:
Yurong Ou, Yanling Zhang, Donghong Yu, Bo Zhu, Zenong Cheng, Lei Zhou, Qiong Zhang, Xiang Yong, Xiaoli Wang, Zhaogen Cai
Publikováno v:
BMC Cancer
BACKGROUND: Centrally necrotizing carcinoma of the breast (CNC) represents a newly-identified subset of breast cancer. The clinical and pathological characteristics of this breast cancer subtype are not yet completely understood. METHODS: We assessed
Autor:
Ewan K.A. Millar, Elena A Takano, Alexander Dobrovic, Peter Graham, Jason Li, Stephen B. Fox, Katie T. Huang, Samantha E. Boyle, Thomas Mikeska, Ian G. Campbell, Terence P. Speed
Publikováno v:
BMC Cancer
Background Patients with breast cancer have an increased risk of developing subsequent breast cancers. It is important to distinguish whether these tumours are de novo or recurrences of the primary tumour in order to guide the appropriate therapy. Ou
Autor:
Brittany Singleton, Shawn D. Llopis, Tamika Duplessis, Brian G. Rowan, Christopher Williams, Latonya Carrier
Publikováno v:
BMC Cancer
Background NR4A orphan nuclear receptors are involved in multiple biological processes which are important in tumorigenesis such as cell proliferation, apoptosis, differentiation, and glucose utilization. The significance of NR4A family member NURR1
Autor:
Derek C. Radisky, Armando Manduca, Robert A. Vierkant, Dana H. Whaley, Matthew R. Jensen, Daniel W. Visscher, Kathleen R. Brandt, Ryan D. Frank, Ethan P. Heinzen, Christopher G. Scott, Karthik Ghosh, Lynn C. Hartmann, Celine M. Vachon, Amy C. Degnim, Stacey J. Winham, Marlene H. Frost
Publikováno v:
BMC Cancer
Background Atypical hyperplasia (AH) and mammographic breast density (MBD) are established risk factors for breast cancer (BC), but their joint contributions are not well understood. We examine associations of MBD and BC by histologic impression, inc
Publikováno v:
BMC Cancer
Automated breast volume scanner (ABVS) and US elastography (UE) have been useful for the differentiation of benign and malignant lesions. However, combining these two methods applied in diagnosis of breast lesions has not yet been reported. The aim o
Publikováno v:
BMC Cancer
BMC Cancer, Vol 2, Iss 1, p 22 (2002)
BMC Cancer, Vol 2, Iss 1, p 22 (2002)
Backgroud Bone mineral density (BMD) is a marker of long-term estrogen exposure. BMD measurement has been used in this context to investigate the association of estrogen with breast cancer risk in three cohorts. In order to assess further BMD as a pr
Autor:
Rosette Lidereau, Géraldine Cizeron-Clairac, Ivan Bièche, Céline Callens, Sophie Vacher, François Lallemand
Publikováno v:
BMC Cancer
Background MicroRNAs (miRNAs) show differential expression across breast cancer subtypes and have both oncogenic and tumor-suppressive roles. Numerous microarray studies reported different expression patterns of miRNAs in breast cancers and found cli
Autor:
Anastazia Pazaiti, Theodoros N. Sergentanis, Effstratios Patsouris, Christos Papadimitriou, Afrodite Nonni, George Theodoropoulos, Eleni Zogafos, Philip Domeyer, Andreas C. Lazaris, George C. Zografos, Nikolaos V. Michalopoulos, Flora Zagouri
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 353 (2010)
BMC Cancer
BMC Cancer
Background Hsp90 (heat shock protein90) is a chaperone protein essential for preserving and regulating the function of various cellular proteins. Elevated Hsp90 expression seems to be a trait of breast cancer and may be an integral part of the coping