Zobrazeno 1 - 10
of 31
pro vyhledávání: ''
Autor:
Martha M. Grimes, Yuna Guo, Dayna Dominguez, Laurie G. Hudson, Angela Wandinger-Ness, Kathryn J. Brayer, S. Ray Kenney
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-16 (2021)
BMC Cancer
BMC Cancer
Background Rho-family GTPases, including Ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division control protein 42 (Cdc42), are important modulators of cancer-relevant cell functions and are viewed as promising therapeutic targets. Based
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer
BMC Cancer
Zoledronic acid (ZA) is one of the most important and effective class of anti-resorptive drug available among bisphosphonate (BP), which could effectively reduce the risk of skeletal-related events, and lead to a treatment paradigm for patients with
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
BMC Cancer
BMC Cancer
Background The effect of brachytherapy on lymphocytes and cytokines in the tumor microenvironment is unclear. This study aimed to analyze the relationship between the invasion of lymphocytes and cytokines in the tumor microenvironment and the interva
Autor:
Abeer A. Almiman, Julian Ramelow, Christopher Brooks, Miguel A. Villalona-Calero, Terence M. Williams, Wenrui Duan, Li Gao
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer
BMC Cancer
Background Lung cancer is the number one cancer killer worldwide. A major drawback in the lung cancer treatment field is the lack of realistic mouse models that replicate the complexity of human malignancy and immune contexture within the tumor micro
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
BMC Cancer
BMC Cancer
Background Pancreatic cancer is characterized by a highly immunosuppressive tumor microenvironment and evasion of immune surveillance. Although programmed cell death 1 receptor (PD-1) blockade has achieved certain success in immunogenic cancers, the
Autor:
Angelo Sparaneo, Reza Bayat Mokhtari, Sushil Kumar, Herman Yeger, Narges Baluch, Evgeniya Morgatskaya, Hai Ling Cheng, Sheyun Zhao, Bikul Das, Lucia Anna Muscarella
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-19 (2019)
BMC Cancer
BMC Cancer
Background Bronchial carcinoids are neuroendocrine tumors that present as typical (TC) and atypical (AC) variants, the latter being more aggressive, invasive and metastatic. Studies of tumor initiating cell (TIC) biology in bronchial carcinoids has b
Autor:
Samantha J. Van Nest, Andrew Jirasek, Julian J. Lum, Alexandre G. Brolo, Mathew N. Hindi, Nils Pavey, Leah M. Nicholson
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
BMC Cancer
BMC Cancer
Background Radiation therapy is a standard form of treating non-small cell lung cancer, however, local recurrence is a major issue with this type of treatment. A better understanding of the metabolic response to radiation therapy may provide insight
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
BMC Cancer
BMC Cancer
Background Different strains of Newcastle disease virus (NDV) worldwide proved to have tumouricidal activity in several types of cancer cells. However, the possible anti-cancer activity of Malaysian NDV AF2240 strain and its mechanism of action remai
Autor:
Afroz S. Mohammad, Jessica Griffith, Chris E. Adkins, Neal Shah, Rawaa Aljammal, Katherine L. Jarrell, Rachel M. Tallman, Paul R. Lockman
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
BMC Cancer
BMC Cancer
Background Brain tumor vasculature can be significantly compromised and leakier than that of normal brain blood vessels. Little is known if there are vascular permeability alterations in the brain adjacent to tumor (BAT). Changes in BAT permeability
Autor:
Asunción Martín-Ruiz, Laura Peña, J. C. Illera, Sara Caceres, A. González-Gil, Lucía Teresa Díez-Córdova
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
BMC Cancer
BMC Cancer
Background Indole-3-carbinol, derived from Cruciferous vegetables is an estrogen receptor antagonist considered a preventive agent that is naturally present in diet. There are no previous studies on its effects in human inflammatory breast cancer or